EC Number |
Recommended Name |
Source Tissue |
Reference |
---|
2.3.1.23 | 1-acylglycerophosphocholine O-acyltransferase |
cerebral cortex |
anterior and posterior |
755989 |
2.3.1.67 | 1-alkylglycerophosphocholine O-acetyltransferase |
cerebral cortex |
- |
487384, 487393 |
2.7.1.68 | 1-phosphatidylinositol-4-phosphate 5-kinase |
cerebral cortex |
- |
738165 |
2.7.1.149 | 1-phosphatidylinositol-5-phosphate 4-kinase |
cerebral cortex |
isoform PI5P4Kbeta is expressed in neuronal populations, especially hippocampus and cortex |
759554 |
1.1.1.315 | 11-cis-retinol dehydrogenase |
cerebral cortex |
5% mRNA expression of Rdh5 compared to liver |
690797 |
1.1.1.62 | 17beta-estradiol 17-dehydrogenase |
cerebral cortex |
moderate expression |
685803 |
1.2.1.105 | 2-oxoglutarate dehydrogenase system |
cerebral cortex |
- |
673870, 762740 |
1.1.1.149 | 20alpha-hydroxysteroid dehydrogenase |
cerebral cortex |
- |
763094 |
3.1.4.53 | 3',5'-cyclic-AMP phosphodiesterase |
cerebral cortex |
- |
678086 |
3.1.4.35 | 3',5'-cyclic-GMP phosphodiesterase |
cerebral cortex |
- |
691558 |
3.1.4.17 | 3',5'-cyclic-nucleotide phosphodiesterase |
cerebral cortex |
external layer of |
670448 |
1.1.1.178 | 3-hydroxy-2-methylbutyryl-CoA dehydrogenase |
cerebral cortex |
- |
673530 |
1.2.4.4 | 3-methyl-2-oxobutanoate dehydrogenase (2-methylpropanoyl-transferring) |
cerebral cortex |
- |
725082 |
1.3.99.5 | 3-oxo-5alpha-steroid 4-dehydrogenase (acceptor) |
cerebral cortex |
prefrontal, expression of isozymes 5alpha-R1 and 5alpha-R2 |
655526 |
1.1.1.357 | 3alpha-hydroxysteroid 3-dehydrogenase |
cerebral cortex |
- |
763094 |
1.1.1.278 | 3beta-hydroxy-5alpha-steroid dehydrogenase |
cerebral cortex |
activity below detection limit of 0.1 fmol/mg protein/min |
639089 |
2.6.1.19 | 4-aminobutyrate-2-oxoglutarate transaminase |
cerebral cortex |
- |
738349 |
3.1.3.41 | 4-nitrophenylphosphatase |
cerebral cortex |
- |
682284 |
3.1.3.5 | 5'-nucleotidase |
cerebral cortex |
- |
679085, 682113, 692192 |
3.1.3.5 | 5'-nucleotidase |
cerebral cortex |
synaptosome |
707925 |
6.2.1.16 | acetoacetate-CoA ligase |
cerebral cortex |
in cerebral cortex expression of AACS mRNA is restricetd to neuronal cells |
661256 |
3.1.1.7 | acetylcholinesterase |
cerebral cortex |
- |
653365, 679180, 682110, 682902, 694391 |
3.1.2.20 | acyl-CoA hydrolase |
cerebral cortex |
- |
646125, 646126, 646167 |
3.1.1.23 | acylglycerol lipase |
cerebral cortex |
- |
650849, 653676 |
3.4.24.B10 | ADAM12 endopeptidase |
cerebral cortex |
fetal |
670683 |
3.5.4.4 | adenosine deaminase |
cerebral cortex |
- |
695973, 711695 |
2.7.1.20 | adenosine kinase |
cerebral cortex |
- |
676193 |
4.6.1.1 | adenylate cyclase |
cerebral cortex |
- |
691561 |
4.6.1.1 | adenylate cyclase |
cerebral cortex |
ACIII localizes to cilia in adults, throughout the cortex, including the subiculum, as well as the retrosplenial granular, visual, motor, and orbital cortices |
-, 681092 |
3.6.1.13 | ADP-ribose diphosphatase |
cerebral cortex |
- |
209946, 655991 |
3.5.3.11 | agmatinase |
cerebral cortex |
agmatinase is localised pre- and postsynaptically, to dendritic spines, spine and non-spine terminals, and dendritic profiles. In dendritic spines, labelling displayed a tendency towards the postsynaptic density |
718561 |
1.2.3.1 | aldehyde oxidase |
cerebral cortex |
- |
390422 |
1.1.1.21 | aldose reductase |
cerebral cortex |
- |
-, 739113 |
1.14.16.5 | alkylglycerol monooxygenase |
cerebral cortex |
- |
688220 |
2.3.1.105 | alkylglycerophosphate 2-O-acetyltransferase |
cerebral cortex |
- |
486104, 486105 |
3.2.1.28 | alpha,alpha-trehalase |
cerebral cortex |
strong trehalase activity |
750882 |
2.4.3.8 | alpha-N-acetylneuraminate alpha-2,8-sialyltransferase |
cerebral cortex |
- |
639661, 723273, 759644, 760219 |
3.4.11.6 | aminopeptidase B |
cerebral cortex |
- |
35972, 682114 |
3.4.17.23 | angiotensin-converting enzyme 2 |
cerebral cortex |
- |
679707 |
3.4.17.23 | angiotensin-converting enzyme 2 |
cerebral cortex |
about 10% of the ACE2 gene expression in kidney cortex |
668896 |
3.6.1.5 | apyrase |
cerebral cortex |
- |
757465 |
3.6.1.5 | apyrase |
cerebral cortex |
increase in enzymic activity from birth to day 30, decrease afterwards, highest enzymic activity at day 30, highest affinity for enzyme at day 365, relative abundance of enzyme is highest at day 15 of ontogeny |
668983 |
1.13.11.34 | arachidonate 5-lipoxygenase |
cerebral cortex |
- |
-, 689167 |
4.1.1.19 | arginine decarboxylase |
cerebral cortex |
presence of both arginine decarboxylase and arginase in principal neurons and putative interneurons |
728614 |
4.3.2.1 | argininosuccinate lyase |
cerebral cortex |
- |
708319 |
3.1.1.2 | arylesterase |
cerebral cortex |
- |
35206 |
3.1.6.1 | arylsulfatase (type I) |
cerebral cortex |
activity increases gradually during development |
135532 |
3.1.6.1 | arylsulfatase (type I) |
cerebral cortex |
no significant changes in enzyme level upon feeding ethanol-containing Lieber-DeCarli liquid diet |
677433 |
5.1.1.13 | aspartate racemase |
cerebral cortex |
- |
706558, 728034 |
2.7.11.15 | beta-adrenergic-receptor kinase |
cerebral cortex |
- |
490911, 640698, 640709, 645000, 645003, 645005 |
2.7.11.15 | beta-adrenergic-receptor kinase |
cerebral cortex |
brain: highest beta-ARK mRNA concentrations in cerebral cortex and cerebellum |
490985 |
2.7.11.15 | beta-adrenergic-receptor kinase |
cerebral cortex |
highest beta-ARK activity |
645001 |
2.4.3.1 | beta-galactoside alpha-(2,6)-sialyltransferase |
cerebral cortex |
- |
637272 |
2.4.1.38 | beta-N-acetylglucosaminylglycopeptide beta-1,4-galactosyltransferase |
cerebral cortex |
- |
687078 |
3.2.1.52 | beta-N-acetylhexosaminidase |
cerebral cortex |
in affected cats with GM2 gangliosidosis, hexosaminidase beta-subunit mRNA levels are approximately 1.5times higher than normal, while beta-subunit protein levels are substantially reduced |
700234 |
2.1.1.5 | betaine-homocysteine S-methyltransferase |
cerebral cortex |
BHMT expression is observed in the amygdala of basal ganglia and the cerebral cortex where BHMT levels are clearly elevated during torpor |
735112 |
1.3.1.24 | biliverdin reductase |
cerebral cortex |
- |
725769 |
1.2.1.25 | branched-chain alpha-keto acid dehydrogenase system |
cerebral cortex |
- |
763513 |
2.6.1.42 | branched-chain-amino-acid transaminase |
cerebral cortex |
- |
673846 |
2.7.11.17 | Ca2+/calmodulin-dependent protein kinase |
cerebral cortex |
- |
694396, 694403, 705904, 761014 |
2.7.11.17 | Ca2+/calmodulin-dependent protein kinase |
cerebral cortex |
cerebral cortical neuronal nucleus |
694382 |
2.7.11.17 | Ca2+/calmodulin-dependent protein kinase |
cerebral cortex |
isozymes CaMKIdelta and CaMKIalpha |
676188 |
3.4.22.52 | calpain-1 |
cerebral cortex |
- |
643998, 680913 |
3.4.17.1 | carboxypeptidase A |
cerebral cortex |
- |
667459, 668122 |
3.4.17.15 | carboxypeptidase A2 |
cerebral cortex |
- |
667459 |
2.3.1.7 | carnitine O-acetyltransferase |
cerebral cortex |
strong activity |
720292 |
3.4.22.56 | caspase-3 |
cerebral cortex |
- |
699679 |
3.4.22.61 | caspase-8 |
cerebral cortex |
ipsilateral side |
697809 |
3.4.22.62 | caspase-9 |
cerebral cortex |
mitochondrial fraction of cerebral tissue, hypoxia-treated, classified into a normoxic group and a hypoxic group |
700460 |
3.4.22.62 | caspase-9 |
cerebral cortex |
of newborn piglet |
666462 |
3.4.22.62 | caspase-9 |
cerebral cortex |
of newborn piglets |
666456 |
2.1.1.6 | catechol O-methyltransferase |
cerebral cortex |
membrane-bound COMT activities in the cerebral cortex are significantly reduced in high-salt loaded Dahl salt-sensitive rats compared with normal-salt loaded Dahl salt-sensitive rats |
685455 |
3.4.22.1 | cathepsin B |
cerebral cortex |
- |
36638 |
3.4.22.27 | cathepsin S |
cerebral cortex |
- |
697041 |
3.4.18.1 | cathepsin X |
cerebral cortex |
- |
683448 |
3.4.18.1 | cathepsin X |
cerebral cortex |
of healthy individuals and Alzheimer patients |
683448 |
2.7.8.11 | CDP-diacylglycerol-inositol 3-phosphatidyltransferase |
cerebral cortex |
- |
645316 |
3.1.6.8 | cerebroside-sulfatase |
cerebral cortex |
- |
677433 |
2.7.11.12 | cGMP-dependent protein kinase |
cerebral cortex |
predominant expression of isozyme cGKIbeta |
662962 |
1.14.14.25 | cholesterol 24-hydroxylase |
cerebral cortex |
- |
735877 |
1.14.14.25 | cholesterol 24-hydroxylase |
cerebral cortex |
pyramidal neurons |
687987 |
2.3.1.6 | choline O-acetyltransferase |
cerebral cortex |
- |
736678 |
3.1.1.8 | cholinesterase |
cerebral cortex |
- |
730237 |
2.8.2.5 | chondroitin 4-sulfotransferase |
cerebral cortex |
- |
695144 |
2.8.2.17 | chondroitin 6-sulfotransferase |
cerebral cortex |
- |
738897 |
2.3.3.1 | citrate (Si)-synthase |
cerebral cortex |
- |
702966 |
2.7.3.2 | creatine kinase |
cerebral cortex |
- |
-, 705501, 705502, 739050 |
2.7.3.2 | creatine kinase |
cerebral cortex |
in cerebral cortex creatine kinase activity is inhibited 6 and 12 h after renal ischemia. Only N-acetylcysteine or N-acetylcysteine plus deferoxamine are able to prevent the inhibition on the enzyme |
-, 689220 |
2.7.11.22 | cyclin-dependent kinase |
cerebral cortex |
- |
662124, 662688, 664179, 666467, 695204 |
3.4.11.3 | cystinyl aminopeptidase |
cerebral cortex |
- |
669637 |
7.1.1.9 | cytochrome-c oxidase |
cerebral cortex |
- |
686054 |
7.1.1.9 | cytochrome-c oxidase |
cerebral cortex |
frontal cortex and posterior cortex |
695205 |
7.1.1.9 | cytochrome-c oxidase |
cerebral cortex |
regular alternation of areas with high and low levels of activity of the respiratory enzyme CO in layers III, IV, and VI of field 17 and in layers IV and VII of field 18 of the cerebral cortex |
694377 |
3.4.11.14 | cytosol alanyl aminopeptidase |
cerebral cortex |
- |
682118 |
1.4.3.3 | D-amino-acid oxidase |
cerebral cortex |
- |
699164, 723921, 742603 |
1.4.3.1 | D-aspartate oxidase |
cerebral cortex |
- |
743140 |
1.4.3.1 | D-aspartate oxidase |
cerebral cortex |
relatively high enzyme expression just after birth, the content gradually decreases thereafter |
711719 |
2.7.1.107 | diacylglycerol kinase (ATP) |
cerebral cortex |
- |
640358, 640386 |
2.3.1.61 | dihydrolipoyllysine-residue succinyltransferase |
cerebral cortex |
- |
487343 |
1.3.5.2 | dihydroorotate dehydrogenase (quinone) |
cerebral cortex |
high enzyme level |
713150 |