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Search term: cerebral cortex

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EC Number Recommended Name Source Tissue Commentary Reference
Display the word mapDisplay the reaction diagram Show all sequences 3.4.23.45memapsin 1 cerebral cortex samples from frontal cortex of both Alzheimer's disease-affected individuals and age-matched controls. Samples show substantial total amounts of BACE2 protein and enzymatic activity. BACE2 activity does not change significantly in the brain of patients with Alzheimer's disease, and is not related to amyloid beta-peptide concentration 712811
Display the word mapDisplay the reaction diagram Show all sequences 3.4.23.46memapsin 2 cerebral cortex - 678539
Display the word mapDisplay the reaction diagram Show all sequences 3.4.23.46memapsin 2 cerebral cortex samples from frontal cortex of both Alzheimer's disease-affected individuals and age-matched controls. BACE1 activity shows a significant positive correlation with the amount of extractable amyloid beta-peptide, and BACE1 protein and activity are significantly increased in cases of alzheimer's disease 712811
Display the word mapDisplay the reaction diagram Show all sequences 3.4.24.11neprilysin cerebral cortex low level of neprilysin. Amyloid-beta deposition appears in the cerebral cortex and the hippocampus 701381
Display the word mapDisplay the reaction diagram Show all sequences 3.4.24.56insulysin cerebral cortex after the development of first amyloid beta plaques in brain of transgenic mice with alzheimer's disease-like neuropathology, cortical mRNAand protein levels of IDE are significantly up-regulated in the transgenic mice compared to their non-transgenic littermates. Up-regulation of IDE mRNA-levels occurrs in parallel with increased amyloid beta40 and amyloid beta42 production. A significant positive correlation is observed between protein levels of IDE and full-length amyloid precursor protein in the cerebral cortex 700455
Display the word mapDisplay the reaction diagram Show all sequences 3.4.24.56insulysin cerebral cortex in Alzheimer's disease patients the protein level of insulin-degrading enzyme is decreased compared to control. However, mRNA of insulin-degrading enzyme is higher in cortex of Alzheimer's disease patients 753340
Display the word mapDisplay the reaction diagram Show all sequences 3.4.24.56insulysin cerebral cortex isolated brain microvessels, in patients with Alzheimer’s disease with cerebral amyloid angiopathy enzyme protein level is up to 44% increased, but enzyme activity is significantly reduced 667412
Display the word mapDisplay the reaction diagram Show all sequences 3.4.24.71endothelin-converting enzyme 1 cerebral cortex ECE-1 expression in Alzheimer's disease brain shows no significant difference compared with age-matched controls 720290
Display the word mapDisplay the reaction diagram Show all sequences 3.4.24.B10ADAM12 endopeptidase cerebral cortex fetal 670683
Display the word mapDisplay the reaction diagram Show all sequences 3.4.25.1proteasome endopeptidase complex cerebral cortex - 688760
Display the word mapDisplay the reaction diagram Show all sequences 3.4.25.1proteasome endopeptidase complex cerebral cortex from fetal ICR mice 711082
Show all pathways known for 3.5.1.2Display the word mapDisplay the reaction diagram Show all sequences 3.5.1.2glutaminase cerebral cortex isozymes LGA and KGA 670391
Show all pathways known for 3.5.3.11Display the word mapDisplay the reaction diagram Show all sequences 3.5.3.11agmatinase cerebral cortex agmatinase is localised pre- and postsynaptically, to dendritic spines, spine and non-spine terminals, and dendritic profiles. In dendritic spines, labelling displayed a tendency towards the postsynaptic density 718561
Display the word mapDisplay the reaction diagram Show all sequences 3.5.3.15protein-arginine deiminase cerebral cortex - 695453
Display the word mapDisplay the reaction diagram Show all sequences 3.5.3.15protein-arginine deiminase cerebral cortex in neuronal cells of the cerebral cortex 712824
Display the word mapDisplay the reaction diagram Show all sequences 3.5.4.37double-stranded RNA adenine deaminase cerebral cortex spatiotemporal expression patterns for ADAR1 and ADAR2 in mouse forebrain. ADAR1 and ADAR2 are broadly distributed in most regions of the mouse forebrain, including the cerebral cortex, hippocampus, and diencephalon. High expression levels are maintained into adulthood. ADAR1 and ADAR2 are expressed in neurons but not astrocytes. ADAR1 mRNA has its lowest expression in the choroid plexus, cortex and hippocampus, while ADAR2 mRNA is least expressed in the cortex and hippocampus, with increased expression in the thalamus 719335
Show all pathways known for 3.5.4.4Display the word mapDisplay the reaction diagram Show all sequences 3.5.4.4adenosine deaminase cerebral cortex - 695973, 711695
Show all pathways known for 3.6.1.13Display the word mapDisplay the reaction diagram Show all sequences 3.6.1.13ADP-ribose diphosphatase cerebral cortex - 209946, 655991
Display the word mapDisplay the reaction diagram Show all sequences 3.6.1.28thiamine-triphosphatase cerebral cortex - 668963
Show all pathways known for 3.6.1.5Display the word mapDisplay the reaction diagram Show all sequences 3.6.1.5apyrase cerebral cortex - 757465
Show all pathways known for 3.6.1.5Display the word mapDisplay the reaction diagram Show all sequences 3.6.1.5apyrase cerebral cortex increase in enzymic activity from birth to day 30, decrease afterwards, highest enzymic activity at day 30, highest affinity for enzyme at day 365, relative abundance of enzyme is highest at day 15 of ontogeny 668983
Show all pathways known for 3.6.1.9Display the word mapDisplay the reaction diagram Show all sequences 3.6.1.9nucleotide diphosphatase cerebral cortex - 698337
Display the word mapDisplay the reaction diagram Show all sequences 3.6.5.2small monomeric GTPase cerebral cortex of E17 mice -, 755959
Show all pathways known for 4.1.1.15Display the word mapDisplay the reaction diagram Show all sequences 4.1.1.15glutamate decarboxylase cerebral cortex - -, 697807
Show all pathways known for 4.1.1.19Display the word mapDisplay the reaction diagram Show all sequences 4.1.1.19arginine decarboxylase cerebral cortex presence of both arginine decarboxylase and arginase in principal neurons and putative interneurons 728614
Show all pathways known for 4.1.1.22Display the word mapDisplay the reaction diagram Show all sequences 4.1.1.22histidine decarboxylase cerebral cortex - 716351
Show all pathways known for 4.1.2.13Display the word mapDisplay the reaction diagram Show all sequences 4.1.2.13fructose-bisphosphate aldolase cerebral cortex - 651759
Show all pathways known for 4.1.2.13Display the word mapDisplay the reaction diagram Show all sequences 4.1.2.13fructose-bisphosphate aldolase cerebral cortex isoenzyme III, IV, and V 4948
Show all pathways known for 4.1.3.4Display the word mapDisplay the reaction diagram Show all sequences 4.1.3.4hydroxymethylglutaryl-CoA lyase cerebral cortex - 693782
Show all pathways known for 4.3.2.1Display the word mapDisplay the reaction diagram Show all sequences 4.3.2.1argininosuccinate lyase cerebral cortex - 708319
Show all pathways known for 4.3.2.9Display the word mapDisplay the reaction diagram Show all sequences 4.3.2.9gamma-glutamylcyclotransferase cerebral cortex weak expression 720332
Show all pathways known for 4.4.1.5Display the word mapDisplay the reaction diagram Show all sequences 4.4.1.5lactoylglutathione lyase cerebral cortex - 682102
Show all pathways known for 4.6.1.1Display the word mapDisplay the reaction diagram Show all sequences 4.6.1.1adenylate cyclase cerebral cortex - 691561
Show all pathways known for 4.6.1.1Display the word mapDisplay the reaction diagram Show all sequences 4.6.1.1adenylate cyclase cerebral cortex ACIII localizes to cilia in adults, throughout the cortex, including the subiculum, as well as the retrosplenial granular, visual, motor, and orbital cortices -, 681092
Display the word mapDisplay the reaction diagram Show all sequences 4.6.1.2guanylate cyclase cerebral cortex all neocortical areas with high expression of all subunits, expression of the three subunits in all cortical layers, alpha1 subunit enriched in layer VI 681090
Display the word mapDisplay the reaction diagram Show all sequences 4.6.1.2guanylate cyclase cerebral cortex beta1 subunit mRNA widely distributed through all cortical areas and cell layers with higher intensity in layer V, alpha2 mRNA homogeneously distributed through all cortical layers and alpha1 expression higher in layers II–III and V 681090
Show all pathways known for 5.1.1.13Display the word mapDisplay the reaction diagram Show all sequences 5.1.1.13aspartate racemase cerebral cortex - 706558, 728034
Show all pathways known for 5.1.1.18Display the word mapDisplay the reaction diagram Show all sequences 5.1.1.18serine racemase cerebral cortex - -, 706540, 726664, 728034
Show all pathways known for 5.1.1.18Display the word mapDisplay the reaction diagram Show all sequences 5.1.1.18serine racemase cerebral cortex glial culture from 663264
Show all pathways known for 5.1.1.18Display the word mapDisplay the reaction diagram Show all sequences 5.1.1.18serine racemase cerebral cortex pyramidal neuron of cerebral cortex and hippocampal CA1 region, predominant localization 693369
Display the word mapDisplay the reaction diagram Show all sequences 5.6.1.1microtubule-severing ATPase cerebral cortex - 675537, 699690
Display the word mapDisplay the reaction diagram Show all sequences 5.6.1.2dynein ATPase cerebral cortex - 669959
Display the word mapDisplay the reaction diagram Show all sequences 5.6.2.1DNA topoisomerase cerebral cortex neuron 3800
Display the word mapDisplay the reaction diagram Show all sequences 6.1.1.18glutamine-tRNA ligase cerebral cortex - 743985
Show all pathways known for 6.1.1.2Display the word mapDisplay the reaction diagram Show all sequences 6.1.1.2tryptophan-tRNA ligase cerebral cortex about 0.2% of total soluble protein 306
Display the word mapDisplay the reaction diagram Show all sequences 6.2.1.16acetoacetate-CoA ligase cerebral cortex in cerebral cortex expression of AACS mRNA is restricetd to neuronal cells 661256
Show all pathways known for 6.2.1.4Display the word mapDisplay the reaction diagram Show all sequences 6.2.1.4succinate-CoA ligase (GDP-forming) cerebral cortex - 745246
Show all pathways known for 6.3.1.2Display the word mapDisplay the reaction diagram Show all sequences 6.3.1.2glutamine synthetase cerebral cortex - 692128
Display the word mapDisplay the reaction diagram Show all sequences 6.3.2.24tyrosine-arginine ligase cerebral cortex - -, 745971
Display the word mapDisplay the reaction diagram Show all sequences 6.3.2.41N-acetylaspartylglutamate synthase cerebral cortex - 728179
Show all pathways known for 7.1.1.2Display the word mapDisplay the reaction diagram Show all sequences 7.1.1.2NADH:ubiquinone reductase (H+-translocating) cerebral cortex - 692231
Show all pathways known for 7.1.1.9Display the word mapDisplay the reaction diagram Show all sequences 7.1.1.9cytochrome-c oxidase cerebral cortex - 686054
Show all pathways known for 7.1.1.9Display the word mapDisplay the reaction diagram Show all sequences 7.1.1.9cytochrome-c oxidase cerebral cortex frontal cortex and posterior cortex 695205
Show all pathways known for 7.1.1.9Display the word mapDisplay the reaction diagram Show all sequences 7.1.1.9cytochrome-c oxidase cerebral cortex regular alternation of areas with high and low levels of activity of the respiratory enzyme CO in layers III, IV, and VI of field 17 and in layers IV and VII of field 18 of the cerebral cortex 694377
Display the word mapDisplay the reaction diagram Show all sequences 7.2.2.13Na+/K+-exchanging ATPase cerebral cortex - 246958, 246966, 688017, 690001, 695408, 700430, 701165
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