EC Explorer
[browse EC tree] - [search]
EC 1.14.11.41 Details
show Brenda entryEC number
1.14.11.41
Accepted name
L-arginine hydroxylase
Reaction
L-arginine + 2-oxoglutarate + O2 = (3S)-3-hydroxy-L-arginine + succinate + CO2
Other name(s)
VioC (ambiguous),
L-arginine,2-oxoglutarate:O2 oxidoreductase (3-hydroxylating)
Systematic name
L-arginine,2-oxoglutarate:oxygen oxidoreductase (3-hydroxylating)
Comment
Fe2+-dependent enzyme. The enzyme is involved in the biosynthesis of the cyclic pentapeptide antibiotic viomycin. It differs from EC 1.14.20.7, 2-oxoglutarate/L-arginine monooxygenase/decarboxylase (succinate-forming), because it does not form guanidine and (S)-1-pyrroline-5-carboxylate from 3-hydroxy-L-arginine.
History
created 2013
back to topEC Tree
1 Oxidoreductases
1.1 Acting on the CH-OH group of donors
1.14.11.5 created 1972, deleted 1976
