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EC 1.3.1.99 Details
EC number
1.3.1.99
Accepted name
(S)-8-oxocitronellyl enol synthase
Reaction
(S)-8-oxocitronellyl enol + NAD(P)+ = (6E)-8-oxogeranial + NAD(P)H + H+
Other name(s)
CrISY,
8-oxogeranial:NAD(P)+ oxidoreductase (cyclizing, cis,trans-nepetalactol forming),
iridoid synthase (incorrect)
Systematic name
(S)-8-oxocitronellyl enol:NAD(P)+ oxidoreductase
Comment
Isolated from the plants Catharanthus roseus, Olea europaea (common olive), and several Nepeta species. The enzyme reduces 8-oxogeranial, generating an unstable product that is subsequently cyclized into several possible products, either non-enzymically or by dedicated cyclases. The products, known as iridoids, are involved in the biosynthesis of many indole alkaloids. cf. EC 1.3.1.123, 7-epi-iridoid synthase.
History
created 2013, deleted 2019
EC Tree
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![](./taxonomy2/inc/tree/images/tree_continue.png)
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