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EC 1.1.1.324 Details
EC number
1.1.1.324
Accepted name
8-hydroxygeraniol dehydrogenase
Reaction
(6E)-8-hydroxygeraniol + 2 NADP+ = (6E)-8-oxogeranial + 2 NADPH + 2 H+ (overall reaction);;(1a) (6E)-8-hydroxygeraniol + NADP+ = (6E)-8-hydroxygeranial + NADPH + H+;;(1b) (6E)-8-hydroxygeraniol + NADP+ = (6E)-8-oxogeraniol + NADPH + H+ ;;(1c) (6E)-8-hydroxygeranial + NADP+ = (6E)-8-oxogeranial + NADPH + H+ ;;(1d) (6E)-8-oxogeraniol + NADP+ = (6E)-8-oxogeranial + NADPH + H+
Other name(s)
8-hydroxygeraniol oxidoreductase,
CYP76B10,
G10H,
CrG10H,
SmG10H,
acyclic monoterpene primary alcohol:NADP+ oxidoreductase
Systematic name
(6E)-8-hydroxygeraniol:NADP+ oxidoreductase
Comment
Contains Zn2+. The enzyme catalyses the oxidation of (6E)-8-hydroxygeraniol to (6E)-8-oxogeranial via either (6E)-8-hydroxygeranial or (6E)-8-oxogeraniol. Also acts on geraniol, nerol and citronellol. May be identical to EC 1.1.1.183 geraniol dehydrogenase. The recommended numbering of geraniol gives 8-hydroxygeraniol as the substrate rather than 10-hydroxygeraniol as used by references 1 and 2. See prenol nomenclature Pr-1.
History
created 2012
EC Tree
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