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EC 1.17.1.9 Details
show Brenda entryEC number
1.17.1.9
Accepted name
formate dehydrogenase
Reaction
formate + NAD+ = CO2 + NADH
Other name(s)
formate-NAD+ oxidoreductase,
FDH I,
FDH II,
N-FDH,
formic hydrogen-lyase,
formate hydrogenlyase,
hydrogenlyase,
NAD+-linked formate dehydrogenase,
NAD+-dependent formate dehydrogenase,
formate dehydrogenase (NAD+),
NAD+-formate dehydrogenase,
formate benzyl-viologen oxidoreductase,
formic acid dehydrogenase
Systematic name
formate:NAD+ oxidoreductase
CAS registry number
9028-85-7
Comment
The enzyme from most aerobic organisms is devoid of redox-active centres but that from the proteobacterium Methylosinus trichosporium contains iron-sulfur centres, flavin and a molybdenum centre [3]. Together with EC 1.12.1.2 hydrogen dehydrogenase, forms a system previously known as formate hydrogenlyase.
History
created 1961 as EC 1.2.1.2, transferred 2017 to EC 1.17.1.9
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1 Oxidoreductases
1.1.1 With NAD+ or NADP+ as acceptor
1.1.3.1 created 1961, deleted 1984 1.1.3.25 created 1986, deleted 2005 1.1.3.26 created 1989, deleted 2002 1.1.3.31 created 1992, deleted 2003 1.1.3.32 created 1999, deleted 2002 1.1.3.33 created 1999, deleted 2002 1.1.3.34 created 1999, deleted 2002 1.1.3.35 created 1999, deleted 2002 1.1.3.36 created 1999, deleted 2002
