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EC 2.3.3.8 Details
EC number
2.3.3.8
Accepted name
ATP citrate synthase
Reaction
ADP + phosphate + acetyl-CoA + oxaloacetate = ATP + citrate + CoA
Other name(s)
ATP-citric lyase,
ATP:citrate oxaloacetate-lyase [(pro-S)-CH2COO-→acetyl-CoA] (ATP-dephosphorylating),
acetyl-CoA:oxaloacetate acetyltransferase (isomerizing,
ADP-phosphorylating),
adenosine triphosphate citrate lyase,
citrate cleavage enzyme,
citrate-ATP lyase,
citric cleavage enzyme,
ATP citrate (pro-S)-lyase
Systematic name
acetyl-CoA:oxaloacetate C-acetyltransferase [(pro-S)-carboxymethyl-forming, ADP-phosphorylating]
CAS registry number
9027-95-6
Comment
The enzyme can be dissociated into components, two of which are identical with EC 4.1.3.34 (citryl-CoA lyase) and EC 6.2.1.18 (citrate—CoA ligase).
History
created 1965 as EC 4.1.3.8, modified 1986, transferred 2002 to EC 2.3.3.8
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