EC Explorer
[browse EC tree] - [search]
EC 1.14.21.7 Details
show Brenda entryEC number
1.14.21.7
Accepted name
biflaviolin synthase
Reaction
(1) 2 flaviolin + NADPH + H+ + O2 = 3,3′-biflaviolin + NADP+ + 2 H2O;;(2) 2 flaviolin + NADPH + H+ + O2 = 3,8′-biflaviolin + NADP+ + 2 H2O
Other name(s)
CYP158A2,
CYP 158A2,
cytochrome P450 158A2
Systematic name
flaviolin,NADPH:oxygen oxidoreductase
Comment
This cytochrome-P-450 enzyme, from the soil-dwelling bacterium Streptomyces coelicolor A3(2), catalyses a phenol oxidation C-C coupling reaction, which results in the polymerization of flaviolin to form biflaviolin or triflaviolin without the incorporation of oxygen into the product [1,3]. The products are highly conjugated pigments that protect the bacterium from the deleterious effects of UV irradiation [1].
History
created 2008, deleted 2018
back to topEC Tree
1 Oxidoreductases
1.1 Acting on the CH-OH group of donors
1.4.99.1 D-amino-acid dehydrogenase
