2.6.1.33: dTDP-4-amino-4,6-dideoxy-D-glucose transaminase

This is an abbreviated version!
For detailed information about dTDP-4-amino-4,6-dideoxy-D-glucose transaminase, go to the full flat file.

Reaction

Synonyms

aminotransferase, thymidine diphospho-4-amino-4,6-dideoxyglucose, DesI, SAT, sugar aminotransferase, TDP-4-keto-6-deoxy-D-glucose transaminase, thymidine diphospho-4-amino-4,6-dideoxyglucose aminotransferase, thymidine diphospho-4-amino-6-deoxyglucose aminotransferase, thymidine diphospho-4-keto-6-deoxy-D-glucose transaminase, thymidine diphospho-4-keto-6-deoxy-D-glucose-glutamic transaminase, VioA, WecE

ECTree

     2 Transferases

         2.6 Transferring nitrogenous groups

             2.6.1 Transaminases

                2.6.1.33 dTDP-4-amino-4,6-dideoxy-D-glucose transaminase

Advanced search results

Do not include text mining results

Include results (more...)

Include results (more...)

Results	in table
258	AA Sequence
1	Application
1	CAS Registry Number
4	Cloned(Commentary)
3	Cofactor
1	Crystallization (Commentary)
11	Inhibitors
7	KM Value [mM]
4	Molecular Weight [Da]
3	Natural Substrates/ Products (Substrates)
183	Organism
11	Pathway
3	pH Optimum
1	pH Range
3	Purification (Commentary)
2	Reaction
1	Reaction Type
8	Reference
2	Specific Activity [micromol/min/mg]
2	Storage Stability
23	Substrates and Products (Substrate)
2	Subunits
14	Synonyms
1	Systematic Name
3	Temperature Optimum [°C]
1	Temperature Range [°C]
2	Turnover Number [1/s]

Application

print visible entries

print all entries

Application on EC 2.6.1.33 - dTDP-4-amino-4,6-dideoxy-D-glucose transaminase

Please wait a moment until all data is loaded. This message will disappear when all data is loaded.

top print hide show all columns Go to Application Search

Please wait a moment until the data is sorted. This message will disappear when the data is sorted.

APPLICATION

ORGANISM

UNIPROT

COMMENTARY

LITERATURE

synthesis

Escherichia coli

P27833

engineering of Escherichia coli to divert the flow of carbon flux from glucose-1-phosphate to thymidine diphosphate 4-keto 4,6-dideoxy-D-glucose (dTKDG), an intermediate of various dTDP-sugars. Glucose phosphate isomerase, glucose-6-phosphate dehydrogenase and uridylyltransferase genes are deleted while dTDP-D-glucose synthase and dTDP-Dglucose 4,6-dehydratase are overexpressed to produce a pool of dTKDG in the cell cytosol. The flow of dTKDG is further diverted to dTDP-D-viosamine, dTDP 4-amino 4,6-dideoxy-D-galactose, and dTDP 3-amino 3,6-dideoxy-D-galactose sugars using sugar aminotransferases gerB, wecE, and fdtB, respectively, from different sources. These sugar moieties are transferred to the 3-hydroxyl position of quercetin and kaempferol with the help of Arabidopsis thaliana glycosyltransferase ArGT3

737627