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2.6.1.1: aspartate transaminase

This is an abbreviated version!
For detailed information about aspartate transaminase, go to the full flat file.

Word Map on EC 2.6.1.1

Reaction

L-aspartate
+
2-oxoglutarate
=
oxaloacetate
 +
L-glutamate

Synonyms

2-oxoglutarate-glutamate aminotransferase, AAT, AAT-2, AAT-3, AAT3, aatA, AATase, aatB3, all2340, alr1039, alr2765, alr4853, aminotransferase, aspartate, aoa/coa, AsAT, Asp AT, aspartate alpha-ketoglutarate transaminase, aspartate aminotransferase, aspartate aminotransferase 1, aspartate aminotransferase A, aspartate AT, aspartate transaminase, aspartate, 2-oxoglutarate aminotransferase, aspartate-2-oxoglutarate transaminase, aspartate/(R)-cysteate:2-oxoglutarate aminotransferase, aspartate/tyrosine/phenylalanine pyridoxal-5'-phosphate-dependent aminotransferase, aspartate:2-oxoglutarate amino-transferase, aspartate:2-oxoglutarate aminotransferase, aspartic acid aminotransferase, aspartic aminotransferase, aspartyl aminotransferase, AspAT, AspATSs, aspB, aspC, AspT, AST, AST-Bb, AtPAT, bifunctional aspartate aminotransferase and glutamate/aspartate-prephenate aminotransferase, C-S lyase, CAA1, cAST, Cgl0240, class Ibeta AAT, EcAspAT, GL50803_91056, glutamate oxaloacetate transaminase, glutamate oxaloacetate transaminase 1, glutamate-oxalacetate aminotransferase, glutamate-oxalate transaminase, glutamate-oxaloacetate transaminase 1, glutamic oxalic transaminase, glutamic oxaloacetic transaminase, glutamic-aspartic aminotransferase, glutamic-aspartic transaminase, glutamic-oxalacetic transaminase, glutamic-oxaloacetic transaminase, GOT, GOT (enzyme), GOT1, GOT1L1, GOT2, KAT IV, L-aspartate aminotransferase, L-aspartate transaminase, L-aspartate-2-ketoglutarate aminotransferase, L-aspartate-2-oxoglutarate aminotransferase, L-aspartate-2-oxoglutarate-transaminase, L-aspartate-alpha-ketoglutarate transaminase, L-aspartate:2-oxoglutarate aminotransferase, L-aspartateartate aminotransferase, L-aspartic aminotransferase, L-AspAT, mitAAT, More, oxaloacetate transferase, oxaloacetate-aspartate aminotransferase, Pat, PfAspAT, plastid aspartate aminotransferase, prephenate aminotransferase, protein TT0402, PT-AAT, Rv3722c, Sar2028, SsAspAT, Tb11.02.2740, transaminase A

ECTree

     2 Transferases
         2.6 Transferring nitrogenous groups
             2.6.1 Transaminases
                2.6.1.1 aspartate transaminase

Specific Activity

Specific Activity on EC 2.6.1.1 - aspartate transaminase

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SPECIFIC ACTIVITY [µmol/min/mg]
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
0.00000967
-
enzyme from homogenate
0.00875
-
after 905fold purification
0.015
-
homogenate, mitochondrial enzyme
0.04
-
homogenate, cytoplasmic enzyme
0.06
wild type enzyme, at 37°C
0.061
-
partially purified isozyme AST II
0.11
-
cell extract
0.14
substrates: L-asparagine + 2-oxoglutarate, pH 8, 37°C
0.16
substrates: L-tryptophan + 2-oxoglutarate, pH 8, 37°C
0.28
substrates: L-phenylalanine + 2-oxoglutarate, pH 8, 37°C
0.3
-
pH 7.5, 37°C, enzyme in crude extract
0.459
-
after 30fold purification, mitochondrial enzyme
0.576
-
partially purified cytosolic isozyme
1.41
-
after 35fold purification, cytoplasmic enzyme
1.53
-
purified enzyme
100
dolphin
-
purified cytosolic isozyme
1035
-
purified cAspAT, beta-form
104
after 9.5fold purification, at pH 8.0 and 60°C
108
-
mutant V39L
11
crude extract, at pH 8.0 and 60°C
112.1
-
purified recombinant enzyme
12.92
-
recombinant enzyme in Escherichia coli cells
130
-
purified cytosolic isozyme AAT-2 form 2a
136
-
partially purified enzyme
137.7
-
purified recombinant enzyme
140
-
purified cytosolic isozyme AAT-2 form 2c
150
-
purified, mitochondrial isozyme
151.5
-
mitochondrial isozyme
156
-
mitochondrial fraction
16.87
-
in 50 mM Tris-HCl pH 7.8
170
-
purified enzyme
172
-
purified enzyme
178
-
purified pAspAT, gamma-form
18.8
-
purified mitochondrial isozyme from liver
182
-
forward reaction
2.417
pH 7.4, 37°C
2.5
Torulopsis candida
-
purified enzyme
2.67
substrates: L-aspartate + 2-oxoglutarate, pH 8, 37°C
200
-
purified enzyme
202
-
purified mitochondrial isozyme
210
-
purified apoenzyme
215
-
purified cytosolic isozyme
217
-
purified enzyme
22.37
-
mitochondrial enzyme
22.6
-
purified mitochondrial isozyme from heart
221
-
purified enzyme
228
dolphin
-
purified mitochondrial isozyme
231
-
purified mitochondrial isozyme
232
-
purified recombinant enyme
240
-
purified cytosolic isozyme AAT-2 form 2b
25.3
-
pH 7.5, 37°C, partiall purified enzyme
252
-
purified pAspAT, alpha-form
292.3
Torulopsis candida
-
-
2934
-
recombinant purified isozyme AAT2
322
-
purified pAspAT, beta-form
341
-
supernatant fraction
390
-
purified isozyme AAT-1
403.4
-
purified enzyme
443
-
purified cytosolic isozyme
45.15
-
purified enzyme
450
-
purified isozyme AAT-2
454
-
recombinant purified isozyme AAT1
48.45
-
cytoplasmic enzyme
512
-
purified mAspAT
546.5
Leptosphaeria michotii
-
purified isozyme B
671
-
purified cAspAT, alpha-form
69.4
-
partially purified enzyme
74
-
purified cytosolic isozyme from liver
805.6
Leptosphaeria michotii
-
purified isozyme A
83.5
-
purified cytosolic isozyme from heart
93
-
pH 8.5, 60°C, recombinant enzyme
953
-
purified cAspAT, gamma-form
additional information