2.5.1.97: pseudaminic acid synthase
This is an abbreviated version!
For detailed information about pseudaminic acid synthase, go to the full flat file.
Reaction
Synonyms
NeuB3, PseG, PseI
ECTree
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General Information
General Information on EC 2.5.1.97 - pseudaminic acid synthase
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physiological function
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Campylobacter jejuni and Campylobacter coli are the main causes of bacterial diarrhea worldwide. In all of these pathogenic organisms, the flagellin proteins are heavily glycosylated with pseudaminic acid (the product of the PseI catalyzed reaction). The presence of 5,7-bis(acetylamino)-3,5,7,9-tetradeoxy-L-glycero-alpha-L-manno-2-nonulopyranosonic acid is required for the proper development of the flagella and is thereby necessary for motility in, and invasion of, the host