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2.5.1.128: N4-bis(aminopropyl)spermidine synthase

This is an abbreviated version!
For detailed information about N4-bis(aminopropyl)spermidine synthase, go to the full flat file.

Reaction

2 S-adenosyl 3-(methylsulfanyl)propylamine +

spermidine
= 2 S-methyl-5'-thioadenosine +
N4-bis(aminopropyl)spermidine

Synonyms

BpsA, TK1691

ECTree

     2 Transferases
         2.5 Transferring alkyl or aryl groups, other than methyl groups
             2.5.1 Transferring alkyl or aryl groups, other than methyl groups (only sub-subclass identified to date)
                2.5.1.128 N4-bis(aminopropyl)spermidine synthase

Natural Substrates Products

Natural Substrates Products on EC 2.5.1.128 - N4-bis(aminopropyl)spermidine synthase

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NATURAL SUBSTRATE
NATURAL PRODUCT
REACTION DIAGRAM
ORGANISM
UNIPROT
COMMENTARY
(Substrate) hide
LITERATURE
(Substrate)
COMMENTARY
(Product) hide
LITERATURE
(Product)
REVERSIBILITY
r=reversible
ir=irreversible
?=not specified
2 S-adenosyl 3-(methylthio)propylamine + spermidine
2 S-methyl-5'-thioadenosine + N4-bis(aminopropyl)spermidine
show the reaction diagram
N4-bis(aminopropyl)spermidine is the major polyamine in Thermococcus kodakarensis. The branched-chain polyamine synthesized by BpsA is important for cell growth at 93°C
overall reaction
-
?