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2.4.1.254: cyanidin-3-O-glucoside 2''-O-glucuronosyltransferase

This is an abbreviated version!
For detailed information about cyanidin-3-O-glucoside 2''-O-glucuronosyltransferase, go to the full flat file.

Reaction

UDP-alpha-D-glucuronate
+
cyanidin 3-O-beta-D-glucoside
=
UDP
 +
cyanidin 3-O-(2-O-beta-D-glucuronosyl)-beta-D-glucoside

Synonyms

BpUGAT, BpUGT94B1, UDP-glucuronic acid:anthocyanidin 3-glucoside 2'-O-beta-glucuronosyltransferase, UDP-glucuronic acid:anthocyanin glucuronosyltransferase

ECTree

     2 Transferases
         2.4 Glycosyltransferases
             2.4.1 Hexosyltransferases
                2.4.1.254 cyanidin-3-O-glucoside 2''-O-glucuronosyltransferase

Inhibitors

Inhibitors on EC 2.4.1.254 - cyanidin-3-O-glucoside 2''-O-glucuronosyltransferase

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INHIBITOR
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
IMAGE
Ca2+
0.1 mM, 43% inhibition
Cd2+
0.1 mM, 51% inhibition
Cu2+
0.1 mM, complete inhibition. The observed enzyme inhibition by Cu2+ and Hg2+ may not solely be attributed to their effects on the enzyme itself because these heavy metal ions are known to destroy substrate anthocyanins
Fe2+
0.1 mM, 64% inhibition
Hg2+
0.1 mM, complete inhibition. The observed enzyme inhibition by Cu2+ and Hg2+ may not solely be attributed to their effects on the enzyme itself because these heavy metal ions are known to destroy substrate anthocyanins
NEM
5 mM, pH 7.0, 20°C, 20 min, complete inactivation
UDP
1 mM, complete inhibition
UMP
1 mM, 64% inhibition
UTP
1 mM, 91% inhibition
additional information
no inhibition by 1 mM uridine, 1 mM glucose or 1 mM sodium malonate. The enzyme retains full activity after incubation with 1 mM diethyl pyxrocarbonate at pH 7.0, 20°C for 20 min
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