2.3.2.B16: cyclo-(L-Trp-L-Trp) synthase

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For detailed information about cyclo-(L-Trp-L-Trp) synthase, go to the full flat file.

Word Map on EC 2.3.2.B16

2.3.2.B16

archaeological

highlands

peruvian

pre-columbian

bioarchaeological

andean

diachronic

anthropol

crania

ritual

artist

hemivertebrae

mummy

osteological

mummified

professionalism

radiocarbon

Reaction

Synonyms

amir_4627, CDPS, CWPS1NS1868, CWWS1D46488, CWWS1NB2774, CWWS1NB5414, CWWS1NB5737, CWWS2D46488, cyclo-(L-Trp-L-Leu) synthase, cyclo-(L-Trp-L-Pro) synthase, cyclo-(L-Trp-L-Trp) synthase, cyclodipeptide synthase, DmtB, dmtB1, NascA, NcdA, NozA

ECTree

2 Transferases

2.3 Acyltransferases

2.3.2 Aminoacyltransferases

2.3.2.B16 cyclo-(L-Trp-L-Trp) synthase

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Results	in table
7	AA Sequence
10	Cloned(Commentary)
56	General Information
30	Natural Substrates/ Products (Substrates)
28	Organism
1	pH Optimum
2	Protein Variants
1	Purification (Commentary)
21	Reference
31	Substrates and Products (Substrate)
107	Synonyms
1	Temperature Optimum [°C]

Cloned

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Cloned on EC 2.3.2.B16 - cyclo-(L-Trp-L-Trp) synthase

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gene dmtB1, recombinant expression of the gene cluster dmtB1-dmtC1 from Streptomyces youssoufiensis in Streptomyces coelicolor results in production of cyclic Trp-Pro, cyclic Trp-Val, and cycic Trp-Leu derivatives with a farnesyl group at indole C-3, dubbed pre-drimentines (e.g. pre-drimentine G = (3S,5aS,10bS,11aS)-3-(propan-2-yl)-10b-[(2E,6E)-3,7,11-trimethyldodeca-2,6,10-trien-1-yl]-6,10b,11,11a-tetrahydro-2H-pyrazino[1',2':1,5]pyrrolo[2,3-b]indole-1,4(3H,5aH)-dione)

Streptomyces youssoufiensis

A0A343VTS2

759890

gene ncdA, genetic organization, sequence comparisons and phylogenetic tree, recombinant expression of His-tagged wild-type and mutant enzymes in Escherichia coli strain M15

Nocardiopsis sp. CMB-M0232

A0A0R7QWN6, A0A0R7QX11

758585

gene nozA, genetic organization, sequence comparisons and phylogenetic tree, functional recombinant expression of the noz gene cluster in Streptomyces coelicolor, recombinant expression of His-tagged wild-type and mutant enzymes in Escherichia coli strain M15

Nocardiopsis sp. CMB-M0232

A0A0R7QWN6, A0A0R7QX11

758585

gene SCATT_09020, phylogenetic analysis, recombinant overexpression in Escherichia coli

Streptomyces cattleya

F8JRC6, F8JX03

758682

gene SCATT_42550, phylogenetic analysis, recombinant overexpression in Escherichia coli

Streptomyces cattleya

F8JRC6, F8JX03

758682

gene SLAV_12475, phylogenetic analysis, recombinant overexpression in Escherichia coli

Streptomyces lavendulae

A0A2K8PC82

758682

phylogenetic analysis, recombinant overexpression in Escherichia coli

2 entries

recombinant expression in Streptomyces coelicolor, recombinant expression of the CDPS in Escherichia coli results in accumulation of cyclo(L-tryptophanyl-L-tryptophanyl) as the sole detectable 2,5-diketopiperazine (DKP) product

Streptomyces sp.

759890

recombinant overexpression in Escherichia coli

Streptomyces xanthophaeus

758682