2.3.1.71: glycine N-benzoyltransferase
This is an abbreviated version!
For detailed information about glycine N-benzoyltransferase, go to the full flat file.
Reaction
Synonyms
aralkyl-CoA:glycine N-acyltransferase, benzoyl CoA-amino acid N-acyltransferase, benzoyl-CoA:glycine N-acyltransferase, benzoyltransferase, glycine, GlyAT, glycine N-acyltransferase, GNAT
ECTree
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Reaction
Reaction on EC 2.3.1.71 - glycine N-benzoyltransferase
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sequential reaction mechanism in which the acyl-CoA substrate adds to the enzyme first, glycine adds before CoA leaves and the peptide product dissociates last
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benzoyl-CoA + glycine = CoA + hippurate
residue Glu226 functions to deprotonate glycine, facilitating nucleophilic attack on the acyl-CoA substrate