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2.3.1.48: histone acetyltransferase

This is an abbreviated version!
For detailed information about histone acetyltransferase, go to the full flat file.

Word Map on EC 2.3.1.48

Reaction

acetyl-CoA
+
[protein]-L-lysine
=
CoA
 +
[protein]-N6-acetyl-L-lysine

Synonyms

AAPatA, acetyltransferase, histone, Ada2/Ada3/Gcn5 complex, AIB1, amino acid sensing acetyltransferase, AmiPatA, Amir 5672, ARD1, ARD1 acetyltransferase, arginine methyltransferase A, arginine methyltransferase B, arrest defective 1, arrest defective protein 1 acetyltransferase, At3g14980, ATAC2, ATase1, ATase2, cAMP-regulated protein lysine acetyltransferase, Cbp, CBP histone acetyltransferase, CBP/p300, chameau, circadian locomoter output cycles protein kaput, CLOCK, CREB binding protein, CREB-binding protein, CREBBP, east1, ELO3, ELONGATA3, elongator protein 3, ELP3, enhancer-of-asymmetric leaves-two1, Enok, EP300, Esa1, factor acetyltransferase, FAT, Gcn5, GCN5 family KAT, Gcn5 HAT, GCN5 lysine acetyltransferase, GCN5 N acetyltransferase 5, Gcn5 related N-acetyltransferase, GCN5-like acetyltransferase, GCN5-like enzyme, GCN5-related N-acetyltransferase, Gcn5/PCAF histone acetyltransferase, GCN5b, GCN5L2, general control non-derepressible 5, general control non-repressed protein5, general control nonderepressible 5, general control nonrepressed-protein 5, general control of amino acid synthesis 5, GNAT, GNAT-related histone acetyltransferase complex, GTF3C4, H4 lysine acetyltransferase, HAC1, HAG1, HAG3, HAG4, HAG5, HAM1, HAM2, hARD1, HAT, HAT-B, HAT-B complex, Hat1, Hat1p, Hat2, HatB3.I, HBO1, histone (H4 K16) acetyltransferase, histone acetokinase, histone acetyl transferase, histone acetylase, histone acetyltransferase, histone acetyltransferase 1, histone acetyltransferase AtGCN5, histone acetyltransferase B, histone acetyltransferase Tip60, histone acetyltransferase-1, histone acetyltransferases, histone H3 acetyltransferase, histone H4 acetyltransferase, histone H4 lysine 16 acetyltransferase, histone transacetylase, histone/protein lysine acetyltransferase, HIV-1 Tat-interactive protein, hMOF, Hpa2, Hpa3, human acetylase binding to ORC1, Idm1, K (lysine) acetyltransferase 8, K(lysine) acetyltransferase 8, KAT, KAT10, KAT11, KAT12, KAT13A, KAT13B, KAT13C, KAT13D, KAT2, Kat2A, KAT2A/GCN5, Kat2b, KAT3A, KAT3B, KAT4, KAT5, KAT6, KAT6A, KAT6B, KAT7, KAT8, KAT9, Lsy-12, lysine acetyltransferase, lysine acetyltransferase 2, lysine acetyltransferase 2A, lysine acetyltransferase 2B, lysine acetyltransferase 5, lysine acetyltransferase 8, lysine acetyltransferase complex, lysine acetyltransferase p300, lysine acetyltransferases, lysine-acetyltransferase, Mof, monocytic leukemia zinc finger, monocytic leukemia zinc finger protein, More, Morf, MORF histone acetyltransferase, MOZ, MOZ histone acetyltransferase, Moz related factor, Mst1, MtPat, Myb-binding protein 1A, MYBBP1A, MYST, MYST protein lysine acetyltransferase, MYST-related histone acetyltransferase complex, MYST1, MYST2, MYST3, MYST4, N(alpha)-acetyltransferase 10, N-acetyltransferase, N-terminal acetyltransferase, NAA10, NAT, NAT4, NCoA-1, NCoA-3, NCOAT, Nepsilon-lysine acetyltransferase, NuA4, NuA4 histone acetyltransferase, nuclear cytoplasmicO-GlcNAcase and acetyltransferase, nuclear receptor coactivator 1, nuclear receptor coactivator 3, nucleosome-histone acetyltransferase, Nut1, p/CAF, P/CAF histone acetyltransferase, p160, p300, p300 HAT, p300 histone acetyltransferase, p300/CBP, p300/CBP associated factor, p300/CBP histone acetyltransferase, P300/CBP-associated factor, p300/CBP-associated factor (pCAF), p300HAT, PA4534, Pat, PCAF, PCAF histone acetyltransferase, PF11_0192, PfGCN5, PfGCN5 HAT, Piccolo NuA4 complex, protein acetyl-transferase, protein acetyltransferase, Qkf, regulator of Ty1 transposition protein 109, RmtA, RmtB, RPD3, Rtt109, Rv0998, SAS complex, Sas2, Sas3, SRC1, SRC3, Sven 0867, SvePatA, TAF, TAF1, Tat interacting protein of 60 kDa, Tat-interactive protein, 60 kDa, TBP1, TFIIIC90, tGCN5, TgGCN5b, TgMYST-B, Tip60, tumor suppressor histone H3 lysine 23 acetyltransferase, type B histone acetyltransferase, YfmK, zMoz

ECTree

     2 Transferases
         2.3 Acyltransferases
             2.3.1 Transferring groups other than aminoacyl groups
                2.3.1.48 histone acetyltransferase

Cloned

Cloned on EC 2.3.1.48 - histone acetyltransferase

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CLONED (Commentary)
ORGANISM
UNIPROT
LITERATURE
7 genes coding for putative HATs, DNA and amino acid sequence determination and analysis, genome-wide analysis of HAT and HDAC genes, and phylogenetic analysis, detailed overview
-
analysis and mechanism of gene expression
-
ATAC2, DNA and amino acid sequence determination and analysis, Atac2 fused to two HA and two FLAG tags is stably expressed in nuclei of HEK-293 cells and in murine C2C12 cells
ATAC2, genotyping
-
construction of a plasmid generated to facilitate double homologous recombination to remove the DNA encoding C-terminal transmembrane domain from the genomic locus of TgElp3, transient expression of recombinant YFP-tagged in RHDELTAhx parasites from a vector construct using the tubulin promoter and containing anHXGPRT selection marker
expressed as a His-tagged fusion protein in Escherichia coli
-
expressed in Escherichia coli
expressed in Escherichia coli BL21(DE3) cells
expressed in Escherichia coli BL21-CodonPlus (DE3)-RIL cells
expression in Escherichia coli of SAS complex, consisting of Sas2, Sas4, and Sas5, Sas2 is His-tagged, coexpression
-
expression in HEK-293 cell
-
expression in insect cells
expression of Esa1 gene in Escherichia coli
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expression of full-length MORF and PCAF proteins in Sf9 cells
-
expression of Gcn5 and mutants thereof in Escherichia coli BL21 (DE3)
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expression of Gcn5 protein catalytic domain in Escherichia coli BL21 (DE3)
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expression of GST-tagged enzyme in BSC40 cells via VTF-7 vaccinia virus transfection vector
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expression of His-tagged wild-type and mutant enzymes using the baculovrius transfection system
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expression of His6-tagged enzyme in Spodoptora frugiperda Sf21 cell using the baculovirus infection system
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expression of His6-tagged wild-type and mutant Esa1s in Escherichia coli strain BL21(DE3)
-
expression of isoform a in Escherichia coli
expression of monofluorinated phenylalanine analogues, incorporated into tGCN5, using a phenylalanine auxotrophic Escherichia coli strain AFIQ containing the plasmid IQ, which constitutively expresses the lacIq repressor. Determination of Phe replacement by MALDI-TOF mass spectrometry
-
expression of MORF protein as FLAG-tagged protein in Sf9 insect cells via baculovirus infection, and as Gal4-fusion protein in 293T cells, amino acid sequence
expression of mutant HATG485. Coexpression of HBO1 and Jade-1
-
expression of the catalytic domain of PCAF protein, amino acid residues 493-658, in Escherichia coli BL21 (DE3)
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expression of the GST-tagged enzyme in Escherichia coli
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expression of the His-tagged enzyme bound in the Ada2/Ada3/Gcn5 subcomplex of SAGA or the Piccolo NuA4 complex in Escherichia coli strain BL21(DE3), polycistronic vector, method development, overview
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expression of Tip60 in H-1299 human lung carcinoma cells, leads to increased c-Myc protein stability in the transfected cells
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expression of Tip60 protein, which contains an evolutionary conserved domain with yeast silencing factor, as His-tagged protein in Escherichia coli and as GFP-fusion protein in COS cells
-
expression of wild-type and inactive mutant Tip60 in HeLa cells and 293T cells
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expression of wild-type and mutant enzymes in Spodoptera frugiperda Sf9 cells using the baculovirus expression system, genetic regulation of enzyme expression, overview
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expression of wild-type Sas3 protein and mutants as GST-fusion proteins in Escherichia coli
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gene ARD1, recombinant expression in HEK-293 cells, stable recombinant overexpression of GFP-tagged enzyme in MEF cells, recombinant expression of His-tagged enzyme and of GST-tagged enzyme in Escherichia coli strain BL21
gene dGN5, genetic crosses and phenotype analysis, overview, determination of genetic interaction of dGcn5 and dAda2a
-
gene GCN5, enzyme expression analysis
gene GCN5, quantitative RT-PCR enzyme expression analysis, recombinant ectopical expression of HA-tagged enzyme TgGCN5b
gene GCN5, recombinant expression in HEK-293T cells
gene GCN5B, DNA and amino acid sequence determination and analysis, real-time PCR enzyme expression analysis, recombinant expression of N-terminally HA-tagged enzyme TgGCN5b from parasites overexpressing an ectopic enzyme copy
gene hac1, genetic regulation analysis
-
gene hat1, expression of HA-tagged Hat1, HAT-tagged Hat2 and Myc-tagged Hif1 in yeast cells
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gene KAT2A, recombinant expression in HeLa cells, overexpressed Flag-KAT2A does not associate with SQSTM1
gene Kat2a, recombinant expression of FLAG-tagged enzyme in DN32.D3 cells, interaction of FLAG-tagged GCN5 with HA-tagged EGR2 in transiently transfected DN32.D3 cells by coimmunoprecipitation and immunoblotting
gene KAT2B, in vivo gene expression profiling
gene KAT6B, genotyping in small cell lung cancer cell lines, recombinant expression of GST- and FLAG-tagged KAT6B histone acetyltransferase domain in Escherichia coli
gene KAT7, sequence comparisons, expression analysis
gene NAA10, recombinant expression of His-tagged ARD1/Naa10 in Escherichia coli strain BL21, recombinant expression of GST-tagged enzyme in Escherichia coli strain BL21
gene PA4534, recombinant expression of N-terminally His-tagged enzyme in Escherichia coli strain BL21(DE3)
gene yfmK, recombinant expression of wild-type and mutant enzymes in Escherichia coli strain BL21(DE3)
HAM1 promoter analysis, expression pattern, phylogenetic analysis of MYST proteins, overview
HAM2 promoter analysis, expression pattern, phylogenetic analysis of MYST proteins, overview
HAT-B-p50 gene, DNA sequence analysis, overexpression of enzyme form B 55000 kDa subunit as His-tagged protein in Escherichia coli
in vitro transcription and translation of p300 by rabbit reticulocyte extracts, transient expression of an enzyme-GAL4 reporter gene construct in 293T cells, in HeLa cells, and in KG1 cells
-
MYST1, sequence comparison, phylogenetic tree
overexpression of enzyme domain PCAF amino acid residues 493-658 in Escherichia coli
-
overexpression of enzyme domain tGcn5 consisting of amino acid residues 48-210 in Escherichia coli 834 (DE3)
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overexpression of enzyme domain, tGcn5 consists of amino acid residues 48-210
-
overexpression of enzyme domain, yGcn5 consists of amino acid residues 99-262
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overexpression of recombinant histone acetyltransferase domain of p300/CBP-associated factor, residues 157–657, in Escherichia coli
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PCR-amplification, stable transfection of CHO cells, with myc-tag, overexpressing enzyme
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real-time RT-PCR analysis
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recombinant expression of His-tagged full-length enzyme and catalytic domain in Escherichia coli strain BL21(DE3)
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recombinant expression of His-tagged hARD1/NAA10
recombinant expression of the inducible HA-tagged wild-type enzyme and dominant-negative mutant E703G in Toxoplasma gondii parasites
recombinant p300 is expressed in baculovirus, and K1358A HAT mutant gene is expressed in Escherichia coli BL21
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recombinant PCAF expressed in baculovirus
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stable overexpression of FLAG-tagged MOF-conbtaining complex subunits in HEK293/FRT or HeLa S3 cells, overview
successful expression using Escherichia coli BL-21
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successful expression using Escherichia coli BL-21 by using a His-tagged Ada3 subunit of the yeast Ada2/Ada3/Gcn5 complex
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T7-coupled in vitro transcription and translation of FLAG-tagged enzyme
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