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2.3.1.43: phosphatidylcholine-sterol O-acyltransferase

This is an abbreviated version!
For detailed information about phosphatidylcholine-sterol O-acyltransferase, go to the full flat file.

Word Map on EC 2.3.1.43

Reaction

phosphatidylcholine
+
a sterol
=
1-acylglycerophosphocholine
 +
a sterol ester

Synonyms

acyltransferase, lecithin-cholesterol, cholesterol transacyltransferase, LAT, LCAT, lecithin cholesterol acyl transferase, lecithin cholesterol acyltransferase, lecithin-cholesterol acyl transferase, lecithin-cholesterol acyltransferase, lecithin/cholesterol acyltransferase, lecithin: cholesterol acyltransferase, lecithin:cholesterol acyl-transferase, lecithin:cholesterol acyltransferase, lysolecithin acyltransferase, phospholipid-cholesterol acyltransferase, plasma lecithin-cholesterol acyltransferase, TgLCAT, TGME49_272420

ECTree

     2 Transferases
         2.3 Acyltransferases
             2.3.1 Transferring groups other than aminoacyl groups
                2.3.1.43 phosphatidylcholine-sterol O-acyltransferase

Storage Stability

Storage Stability on EC 2.3.1.43 - phosphatidylcholine-sterol O-acyltransferase

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STORAGE STABILITY
ORGANISM
UNIPROT
LITERATURE
-20°C, 90% of activity is retained, 4 weeks
-
-80°C, purified recombinant enzyme, 1-2 mg/ml protein in phosphate buffer with 10% glycerol, the enzyme retains full activity for at least 6 months and is stable to repeated freeze-thaw cycles
0°C, 30 days
-
4°C, 0.4 mM phosphate buffer, 4 mM 2-mercaptoethanol, under N2, 4 weeks
-
4°C, 100 h
-
4°C, 20% loss of activity, 24 h
-
4°C, 60 days
-
4°C, low ionic strength buffer, under nitrogen, 4 weeks
-