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2.3.1.272: 2-acetylphloroglucinol acetyltransferase

This is an abbreviated version!
For detailed information about 2-acetylphloroglucinol acetyltransferase, go to the full flat file.

Reaction

2 2-acetylphloroglucinol =

2,4-diacetylphloroglucinol
+
phloroglucinol

Synonyms

MAPG acetyltransferase, MAPG Atase, monoacetylphloroglucinol acetyltransferase, PhlA, phlACB, phlB, PhlC

ECTree

     2 Transferases
         2.3 Acyltransferases
             2.3.1 Transferring groups other than aminoacyl groups
                2.3.1.272 2-acetylphloroglucinol acetyltransferase

Inhibitors

Inhibitors on EC 2.3.1.272 - 2-acetylphloroglucinol acetyltransferase

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INHIBITOR
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
IMAGE
2,4-diacetylphloroglucinol
2,4-diacetylphloroglucinol inhibits the forward reaction competitively
Cl-
inhibited by 2 mM Cl-
diethylpyrocarbonate
88% inhibition at 1 mM
Hg2+
complete inhibition at 0.1 mM
p-chloromercuribenzoate
complete inhibition at 1 mM
pyoluteorin
inhibited by 0.05 mM pyoluteorin
additional information
NaCl, MgCl2, CaCl2,FeCl3, ZnCl2, CuCl2, and NiCl2, and various metal chelators (0.5 mM), including 1,10-phenanthroline, 8-hydroxyquinoline, 2,2'-dipyridine, and catechol-3,5-disulfonic acid disodium salt, have almost no effect on enzyme activity. Neither activation nor inhibition is found with thiols (1mM) such as L-cysteine, 2-mercaptoethanol, and dithiothreitol; not inhibited by 2 mM Br- or 2 mM I-, as well as phloroglucinol, acetyl-CoA, and malonyl-CoA
-