Any feedback?
Please rate this page
(all_enzymes.php)
(0/150)

BRENDA support

2.3.1.176: propanoyl-CoA C-acyltransferase

This is an abbreviated version!
For detailed information about propanoyl-CoA C-acyltransferase, go to the full flat file.

Word Map on EC 2.3.1.176

Reaction

3alpha,7alpha,12alpha-trihydroxy-5beta-cholanoyl-CoA
+
propanoyl-CoA
=
CoA
 +
3alpha,7alpha,12alpha-trihydroxy-24-oxo-5beta-cholestanoyl-CoA

Synonyms

3-oxopristanoyl-CoA hydrolase, 3-oxopristanoyl-CoA thiolase, EC 2.3.1.154, HaSCP-2, MsSCP-x/SCP-2 protein, non-specific lipid transfer protein, nsLTP, oxopristanoyl-CoA thiolase, peroxisomal 3-oxoacyl coenzyme A thiolase, peroxisomal thiolase 2, peroxisome sterol carrier protein thiolase, propanoyl-CoA C-acyltransferase, PTE-2, SCP-2, SCP-2/thiolase, SCP-x, Scp2, SCP2L2, SCPc, SCPx, sterol carrier protein 2-like 2, sterol carrier protein 2/3-oxoacyl-CoA thiolase, sterol carrier protein type 2, sterol carrier protein x, sterol carrier protein-2, sterol carrier protein-c, sterol carrier protein-x, sterol carrier protein-x/sterol carrier protein-2, TgSCP2, UMAG_11938

ECTree

     2 Transferases
         2.3 Acyltransferases
             2.3.1 Transferring groups other than aminoacyl groups
                2.3.1.176 propanoyl-CoA C-acyltransferase

Crystallization

Crystallization on EC 2.3.1.176 - propanoyl-CoA C-acyltransferase

Please wait a moment until all data is loaded. This message will disappear when all data is loaded.
CRYSTALLIZATION (Commentary)
ORGANISM
UNIPROT
LITERATURE
NMR spectroscopy and docking simulations reveal that the folds of alpha-helices and beta-sheets interact together to form a hydrophobic cavity with putative entrance and exit openings, which serves as a tunnel for accommodation and transport of lipids
C-terminal sterol carrier protein type 2 (SCP-2) domain of human hydroxysteroid dehydrogenase-like protein 2, to 2.1 A resolution. Space group P3121 (or P3221), with unit-cell parameters a = b = 70.4, c = 60.6 A,  alpha = beta = 90°, gamma = 120°