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2.1.1.370: [histone H3]-lysine4 N-dimethyltransferase

This is an abbreviated version!
For detailed information about [histone H3]-lysine4 N-dimethyltransferase, go to the full flat file.

Reaction

2 S-adenosyl-L-methionine +

a [histone H3]-L-lysine4
= 2 S-adenosyl-L-homocysteine +
a [histone H3]-N6,N6-dimethyl-L-lysine4

Synonyms

MEL, NSD3, PFM13, PRDM16, WHISTLE, WHSC1L1

ECTree

     2 Transferases
         2.1 Transferring one-carbon groups
             2.1.1 Methyltransferases
                2.1.1.370 [histone H3]-lysine4 N-dimethyltransferase

Substrates Products

Substrates Products on EC 2.1.1.370 - [histone H3]-lysine4 N-dimethyltransferase

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SUBSTRATE
PRODUCT                       
REACTION DIAGRAM
ORGANISM
UNIPROT
COMMENTARY
(Substrate) hide
LITERATURE
(Substrate)
COMMENTARY
(Product) hide
LITERATURE
(Product)
Reversibility
r=reversible
ir=irreversible
?=not specified
S-adenosyl-L-methionine + a [histone H3]-L-lysine4
S-adenosyl-L-homocysteine + a [histone H3]-N6-methyl-L-lysine4
show the reaction diagram
-
-
-
?
S-adenosyl-L-methionine + a [histone H3]-N6-methyl-L-lysine4
S-adenosyl-L-homocysteine + a [histone H3]-N6,N6-dimethyl-L-lysine4
show the reaction diagram
-
-
-
?
S-adenosyl-L-methionine + [histone H3]-L-lysine4
S-adenosyl-L-homocysteine + [histone H3]-N6-methyl-L-lysine4
show the reaction diagram
-
-
-
?
S-adenosyl-L-methionine + [histone H3]-N6-methyl-L-lysine4
S-adenosyl-L-homocysteine + [histone H3]-N6,N6-dimethyl-L-lysine4
show the reaction diagram
-
-
-
?
additional information
?
-