2.1.1.35: tRNA (uracil54-C5)-methyltransferase

This is an abbreviated version!
For detailed information about tRNA (uracil54-C5)-methyltransferase, go to the full flat file.

Reaction

Synonyms

5-methyluridine 54 tRNA methyltransferase, m5U 54 tRNA methyltransferase, m5U 54 tRNA MTase, m5U methyltransferase, m5U-methyltransferase, methyltransferase, transfer ribonucleate uracil 5-, PAB0719, PAB0719 enzyme, PabTrmU54, ribothymidyl synthase, rTase, RumA, RumA-type tRNA(uracil-54, C5)-methyltransferase, RUMT, S-adenosyl-L-methionine-dependent tRNA (uracil-54, C5)-methyltransferase, transfer RNA uracil 5-methyltransferase, transfer RNA uracil methylase, TrmA, TRMT2A, tRNA (uracil-54, C5)-methyltransferase, tRNA uracil 5-methyltransferase, tRNA(m5U54)methyltransferase, tRNA(uracil-5-)methyltransferase

ECTree

     2 Transferases

         2.1 Transferring one-carbon groups

             2.1.1 Methyltransferases

                2.1.1.35 tRNA (uracil54-C5)-methyltransferase

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Results	in table
9	Activating Compound
8744	AA Sequence
3	Application
1	CAS Registry Number
12	Cloned(Commentary)
30	Cofactor
2	Crystallization (Commentary)
19	Disease/ Diagnostics
1	General Information
2	General Stability
42	Inhibitors
4	Ki Value [mM]
23	KM Value [mM]
9	Localization
12	Metals/Ions
13	Molecular Weight [Da]
27	Natural Substrates/ Products (Substrates)
2	Organic Solvent Stability
102	Organism
2	PDB ID
10	pH Optimum
1	pH Range
13	Protein Variants
18	Purification (Commentary)
16	Reaction
3	Reaction Type
45	Reference
2	Source Tissue
8	Specific Activity [micromol/min/mg]
6	Storage Stability
152	Substrates and Products (Substrate)
12	Subunits
26	Synonyms
1	Systematic Name
20	Temperature Optimum [°C]
1	Temperature Stability [°C]
10	Turnover Number [1/s]

Disease

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Disease on EC 2.1.1.35 - tRNA (uracil54-C5)-methyltransferase

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DISEASE

TITLE OF PUBLICATION

LINK TO PUBMED

Breast Neoplasms

The expression of TRMT2A, a novel cell cycle regulated protein, identifies a subset of breast cancer patients with HER2 over-expression that are at an increased risk of recurrence.

20307320

Leukemia

One-tube and one-buffer system of RT-PCR amplification of 1D gene of foot-and-mouth disease virus field isolates.

9385403

Leukemia

T-cell lymphoma induction by radiation leukemia virus in athymic nude mice.

214507

Neoplasms

Expression of cytokine mRNA in gastric mucosa with Helicobacter pylori infection.

9053967

Osteosarcoma

Serological characterization of a purified reverse transcriptase from osteosarcoma of a child.

92361

Primary Myelofibrosis

Serological characterization of a purified reverse transcriptase from osteosarcoma of a child.

92361

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