2.1.1.233: [phosphatase 2A protein]-leucine-carboxy methyltransferase

This is an abbreviated version!
For detailed information about [phosphatase 2A protein]-leucine-carboxy methyltransferase, go to the full flat file.

Word Map on EC 2.1.1.233

2.1.1.233

demethylation

holoenzyme

methylesterase-1

methylesterification

tauopathies

Reaction

[phosphatase 2A protein]-leucine methyl ester

Synonyms

C-terminal leucine protein carboxyl methyltransferase-1, LCMT-1, LCMT1, leucine carboxy methyltransferase-1, leucine carboxyl methyl transferase 1, leucine carboxyl methyltransferase, leucine carboxyl methyltransferase 1, leucine carboxyl methyltransferase 1 homolog, leucine carboxyl methyltransferase-1, leucine carboxylmethyltransferase-1, leucine carboxymethyltransferase 1/phosphatase methylesterase 1, phosphatase 2A protein methyltransferase, PME-1, PP2A LCMT, PP2A methyltransferase, PP2A-methyltransferase, PP2A-specific methyltransferase, PPM1, Ppm1p, PPMT, protein phosphatase 2A leucine carboxyl methyltransferase, protein phosphatase methyltransferase 1

ECTree

2 Transferases

2.1 Transferring one-carbon groups

2.1.1 Methyltransferases

2.1.1.233 [phosphatase 2A protein]-leucine-carboxy methyltransferase

Advanced search results

Do not include text mining results

Include

results (more...)

Include

results (more...)

Results	in table
1	Activating Compound
3696	AA Sequence
7	Cloned(Commentary)
11	Cofactor
3	Crystallization (Commentary)
110	Disease/ Diagnostics
2	Expression
41	General Information
1	IC50 Value
2	Inhibitors
1	KM Value [mM]
11	Localization
5	Molecular Weight [Da]
17	Natural Substrates/ Products (Substrates)
28	Organism
1	pH Optimum
1	pI Value
13	Protein Variants
7	Purification (Commentary)
1	Reaction
28	Reference
48	Source Tissue
2	Specific Activity [micromol/min/mg]
37	Substrates and Products (Substrate)
5	Subunits
65	Synonyms
1	Systematic Name
1	Temperature Optimum [°C]

Localization

print visible entries

print all entries

Localization on EC 2.1.1.233 - [phosphatase 2A protein]-leucine-carboxy methyltransferase

Please wait a moment until all data is loaded. This message will disappear when all data is loaded.

top print hide

Go to Localization Search

the enzyme is underrepresented in the nucleus and mainly localized to the cytoplasm, Golgi region and late endosomes

the enzyme is underrepresented in the nucleus and mainly localized to the cytoplasm, Golgi region and late endosomes

the enzyme is underrepresented in the nucleus and mainly localized to the cytoplasm, Golgi region and late endosomes

LCMT1 and methylated phosphatase 2A protein are concentrated in rafts, whereas demethylated phosphatase 2A protein and small amounts of PME-1 are preferentially distributed in non-raft membrane microdomains

5886

736425