2.1.1.122: (S)-tetrahydroprotoberberine N-methyltransferase
This is an abbreviated version!
For detailed information about (S)-tetrahydroprotoberberine N-methyltransferase, go to the full flat file.
Reaction
Synonyms
(S)-tetrahydroprotoberberine cis-N-methyltransferase, (S)-Tetrahydroprotoberberine-cis-N-methyltransferase, Methyltransferase, tetrahydroberberine N-, S-Adenosyl-L-methionine: (S)-7,8,13,14-tetrahydroberberine-cis-N-methyltransferase, S-Adenosyl-L-methionine:tetrahydroberberine-cis-N-methyltransferase, S-adenosyl-L-methionine:tetrahydroprotoberberine cis-N-methyltransferase, S-Adenosylmethionine:tetrahydroberberine-N-methyltransferase, Tetrahydroberberine cis-N-methyltransferase, TNMT
ECTree
2.1.1.122 (S)-tetrahydroprotoberberine N-methyltransferaseAdvanced search results
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results (Inhibitors
Inhibitors on EC 2.1.1.122 - (S)-tetrahydroprotoberberine N-methyltransferase
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INHIBITOR 
ORGANISM
UNIPROT
COMMENTARY 
LITERATURE
IMAGE
Mg2+
-
slight increase in activity with increasing concentrations of Mg2+ in sodium phosphate buffer, inhibitory in Hepes buffer
Mn2+
inhibits activity by 41%, inhibition prevented by inclusion of 10 mM EDTA; inhibits TNMT activity by 41%, can be prevented by the inclusion of EDTA
Ni2+
inhibits activity by 72%, inhibition prevented by inclusion of 10 mM EDTA; inhibits TNMT activity by 72%, can be prevented by the inclusion of EDTA
Ca2+
inhibits activity by 62%, inhibition prevented by inclusion of 10 mM EDTA; inhibits TNMT activity by 62%, can be prevented by the inclusion of EDTA
Co2+
inhibits activity by 71%, inhibition prevented by inclusion of 10 mM EDTA; inhibits TNMT activity by 71%, can be prevented by the inclusion of EDTA
