1.3.1.14: dihydroorotate dehydrogenase (NAD+)
This is an abbreviated version!
For detailed information about dihydroorotate dehydrogenase (NAD+), go to the full flat file.
Word Map on EC 1.3.1.14
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1.3.1.14
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pyrimidine
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flavin
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brequinar
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medicine
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l-dihydroorotate
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fmn
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lactis
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o2-sensitive
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mononucleotide
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photons
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bifidobacterium
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bifidum
-
berghei
-
ubiquinone
-
carbamyl
-
half-reaction
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nutrition
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pharmacology
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1.3.3.1
- 1.3.1.14
- pyrimidine
- flavin
- brequinar
- medicine
- l-dihydroorotate
- fmn
- lactis
-
o2-sensitive
- mononucleotide
-
photons
- bifidobacterium
- bifidum
- berghei
- ubiquinone
-
carbamyl
-
half-reaction
- nutrition
- pharmacology
-
1.3.3.1
Reaction
Synonyms
b-type dihydroorotate dehydrogenase, DHO dehydrogenase, DHODase, DHOdehase A, dihydro-orotic dehydrogenase, dihydroorotate dehydrogenase, dihydrorotate dehydrogenase B, L-5,6-dihydro-orotate:NAD oxidoreductase, More, orotate reductase, reductase, orotate
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Natural Substrates Products
Natural Substrates Products on EC 1.3.1.14 - dihydroorotate dehydrogenase (NAD+)
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REACTION DIAGRAM
(S)-dihydroorotate + acceptor
orotate + reduced acceptor
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fourth step in UMP-biosynthesis
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?
orotate + NADH + H+
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fourth step and sole redox reaction in the pyrimidine de novo biosynthetic pathway
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r
dihydroorotate + NAD+
orotate + NADH + H+
-
fourth step and sole redox reaction in the pyrimidine de novo biosynthetic pathway
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r
dihydroorotate + NAD+
orotate + NADH + H+
-
-
breakdown of orotate
r
dihydroorotate + NAD+
orotate + NADH + H+
-
fourth step and sole redox reaction in the pyrimidine de novo biosynthetic pathway
-
r
dihydroorotate + NAD+
orotate + NADH + H+
-
fourth step and sole redox reaction in the pyrimidine de novo biosynthetic pathway
-
r
dihydroorotate + NAD+
orotate + NADH + H+
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biosynthesis of pyrimidines
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?
dihydroorotate + NAD+
orotate + NADH + H+
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enzyme presumably functions mainly in the metabolic synthesis of pyrimidines
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r
dihydroorotate + NAD+
orotate + NADH + H+
-
fourth step and sole redox reaction in the pyrimidine de novo biosynthetic pathway
-
r
dihydroorotate + NAD+
orotate + NADH + H+
-
fourth step and sole redox reaction in the pyrimidine de novo biosynthetic pathway
-
r