1.2.1.47: 4-trimethylammoniobutyraldehyde dehydrogenase
This is an abbreviated version!
For detailed information about 4-trimethylammoniobutyraldehyde dehydrogenase, go to the full flat file.
Word Map on EC 1.2.1.47
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1.2.1.47
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gamma-butyrobetaine
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proliferator-activated
-
dioxygenase
-
peroxisome
-
l-carnitine
-
polyunsaturated
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1.2.1.8
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badhs
-
aldh4a1
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suckling
-
gill
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betaine
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acetaldehyde
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trimethyllysine
- 1.2.1.47
- gamma-butyrobetaine
-
proliferator-activated
-
dioxygenase
- peroxisome
- l-carnitine
-
polyunsaturated
-
1.2.1.8
-
badhs
-
aldh4a1
-
suckling
-
gill
- betaine
- acetaldehyde
- trimethyllysine
Reaction
Synonyms
4-N-trimethylaminobutyraldehyde dehydrogenase, 4-N-trimethylaminobutyraldehyde dehydrogenase II, 4-trimethylaminobutyraldehyde dehydrogenase, 4-trimethylammoniobutyraldehyde dehydrogenase, aldehyde dehydrogenase 9A1, Aldh9a1, carnitine biosynthesis enzyme, dehydrogenase, trimethylaminobutyraldehyde, gamma-trimethylaminobutyraldehyde dehydrogenase, TMABA dehydrogenase, TMABA-DH, TMABADH, TMABAL dehydrogenase, TMABaldehyde-DH II, TMABALDH
ECTree
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Specific Activity
Specific Activity on EC 1.2.1.47 - 4-trimethylammoniobutyraldehyde dehydrogenase
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0.8
12.4
15.4
recombinant enzyme, after 19.5fold purification, at pH 9.5 and 30°C
additional information
expression of TMABA-DH is ontogenically regulated, renal levels of TMABA-DH are quantified by real-time PCR assays in foetuses, newborn, suckling, weaning and 2-month-old rats, foetuses express TMABA-DH mRNA and this expression increases significantly with maturation, comparisons between cortex and medulla reveals that, except for foetuses and newborn rats, TMABA-DHmRNA levels are significantly higher in the medulla than in the cortex
additional information
levels of liver mRNA TMABA-DH are approximately 2times greater than the maximal values measured in kidneys