1.17.8.1: hydroxysqualene dehydroxylase

This is an abbreviated version!
For detailed information about hydroxysqualene dehydroxylase, go to the full flat file.

Reaction

Synonyms

hpnE

ECTree

     1 Oxidoreductases

         1.17 Acting on CH or CH₂ groups

             1.17.8 With a flavin as acceptor

                1.17.8.1 hydroxysqualene dehydroxylase

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72	AA Sequence
2	Cloned(Commentary)
2	Cofactor
2	General Information
2	Organism
1	Pathway
1	Reaction
2	Reference
2	Substrates and Products (Substrate)
3	Synonyms
1	Systematic Name

Systematic Name

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Systematic Name on EC 1.17.8.1 - hydroxysqualene dehydroxylase

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SYSTEMATIC NAME

IUBMB Comments

squalene:FAD oxidoreductase (hydroxylating)

This enzyme, isolated from the bacteria Rhodopseudomonas palustris and Zymomonas mobilis, participates, along with EC 2.5.1.103, presqualene diphosphate synthase, and EC 4.2.3.156, hydroxysqualene synthase, in the conversion of all-trans-farnesyl diphosphate to squalene. Eukaryotes achieve the same goal in a single step, catalysed by EC 2.5.1.21, squalene synthase.