1.14.20.14: hapalindole-type alkaloid chlorinase
This is an abbreviated version!
For detailed information about hapalindole-type alkaloid chlorinase, go to the full flat file.
Word Map on EC 1.14.20.14
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1.14.20.14
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halogenase
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chlorination
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unactivated
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late-stage
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non-heme
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welwitindolinone
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biocatalyst
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structure-guided
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2-oxo-glutarate
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medicine
- 1.14.20.14
- halogenase
-
chlorination
-
unactivated
-
late-stage
-
non-heme
-
welwitindolinone
-
biocatalyst
-
structure-guided
- 2-oxo-glutarate
- medicine
Reaction
Synonyms
ambO5, AmbO5 protein, welO5, WelO5 protein, WelO5*
ECTree
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Crystallization
Crystallization on EC 1.14.20.14 - hapalindole-type alkaloid chlorinase
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hanging drop vapor diffusion method, 2.4 A resolution X-ray crystal structure of WelO5, in complex with its welwitindolinone precursor substrate, 12-epi-fischerindole U and 2.5 A resolution structure of mutant G166D in complex with 12-epi-fischerindole U