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1.14.19.76: flavone synthase II

This is an abbreviated version!
For detailed information about flavone synthase II, go to the full flat file.

Word Map on EC 1.14.19.76

Reaction

a flavanone
+
[reduced NADPH-hemoprotein reductase]
+
O2
=
a flavone
+
[oxidized NADPH-hemoprotein reductase]
+ 2 H2O

Synonyms

AFNS2, CYP93B16, CYP93B2, CYP93G1, CYP93G2, cytochrome P450 93G1, DvFNS, flavone synthase II, FNS II, FNSII, OsFNSII, sb02g000220, SbFNSII, TFNS5

ECTree

     1 Oxidoreductases
         1.14 Acting on paired donors, with incorporation or reduction of molecular oxygen
             1.14.19 With oxidation of a pair of donors resulting in the reduction of O2 to two molecules of water
                1.14.19.76 flavone synthase II

General Information

General Information on EC 1.14.19.76 - flavone synthase II

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GENERAL INFORMATION
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
evolution
D3U591
phylogenetic analyses of the subfamily of plant CYP93B enzymes indicate the evolution of a gene encoding a flavone synthase which originally catalyzes the direct conversion of flavanones into flavones, via early gene duplication into a less efficient enzyme with an altered catalytic mechanism. Ultimately, this allows the evolution of the legume-specific isoflavonoid synthase activity
malfunction
the lignin of the fnsII mutant is completely devoid of tricin, indicating that FNSII activity is essential for the deposition of tricin-bound lignin in rice cell walls. The mutant also shows substantially reduced lignin content with decreased syringyl/guaiacyl lignin unit composition. The loss of tricin in the mutant lignin appears to be partially compensated by incorporating naringenin, which is a preferred substrate of OsFNSII. The fnsII mutant is further revealed to have enhanced enzymatic saccharification efficiency, suggesting that the cell wall recalcitrance of grass biomass may be reduced through the manipulation of the flavonoid monomer supply for lignification
metabolism
physiological function