1.14.19.67: salutaridine synthase
This is an abbreviated version!
For detailed information about salutaridine synthase, go to the full flat file.
Word Map on EC 1.14.19.67
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1.14.19.67
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state-specific
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poppy
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papaver
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opium
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salutaridine
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somniferum
- 1.14.19.67
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state-specific
- poppy
-
papaver
-
opium
- salutaridine
- somniferum
Reaction
Synonyms
(R)-reticuline dehydrogenase, (R)-reticuline oxidase (C-C phenol-coupling), CYP719B1, dehydrogenase, (R)-reticuline, EC 1.1.3.35, EC 1.14.21.4, PsSAS, SalSyn, salutaridine synthase
ECTree
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Substrates Products
Substrates Products on EC 1.14.19.67 - salutaridine synthase
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REACTION DIAGRAM
(R)-norreticuline + [reduced NADPH-hemoprotein reductase] + O2
norsalutaridine + [oxidized NADPH-hemoprotein reductase] + H2O
(R)-reticuline + [reduced NADPH-hemoprotein reductase] + O2
salutaridine + [oxidized NADPH-hemoprotein reductase] + 2 H2O
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-
-
?
(R)-reticuline + [reduced NADPH-hemoprotein reductase] + O2
salutaridine + [oxidized NADPH-hemoprotein reductase] + H2O
norsalutaridine + [oxidized NADPH-hemoprotein reductase] + H2O
-
-
-
?
(R)-norreticuline + [reduced NADPH-hemoprotein reductase] + O2
norsalutaridine + [oxidized NADPH-hemoprotein reductase] + H2O
-
-
-
-
?
salutaridine + [oxidized NADPH-hemoprotein reductase] + H2O
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-
-
?
(R)-reticuline + [reduced NADPH-hemoprotein reductase] + O2
salutaridine + [oxidized NADPH-hemoprotein reductase] + H2O
-
-
-
-
?
(R)-reticuline + [reduced NADPH-hemoprotein reductase] + O2
salutaridine + [oxidized NADPH-hemoprotein reductase] + H2O
-
-
-
?
(R)-reticuline + [reduced NADPH-hemoprotein reductase] + O2
salutaridine + [oxidized NADPH-hemoprotein reductase] + H2O
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strictly dependent on NADPH as reducing cofactor and on (R)-configurated reticuline
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?
(R)-reticuline + [reduced NADPH-hemoprotein reductase] + O2
salutaridine + [oxidized NADPH-hemoprotein reductase] + H2O
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formation of salutaridine, a key intermediate in morphine biosynthesis
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?
(R)-reticuline + [reduced NADPH-hemoprotein reductase] + O2
salutaridine + [oxidized NADPH-hemoprotein reductase] + H2O
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highly regioselective and stereoselective enzyme
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?
(R)-reticuline + [reduced NADPH-hemoprotein reductase] + O2
salutaridine + [oxidized NADPH-hemoprotein reductase] + H2O
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critical step in morphine biosynthesis
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?