1.14.16.5: alkylglycerol monooxygenase
This is an abbreviated version!
For detailed information about alkylglycerol monooxygenase, go to the full flat file.
Word Map on EC 1.14.16.5
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1.14.16.5
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alkylglycerols
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tetrahydrobiopterin
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hydroxylases
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bh4
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tetrahydrobiopterin-dependent
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biopterin
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pterins
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tetrahydropterins
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dihydropteridine
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phenylketonuria
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sepiapterin
- 1.14.16.5
- alkylglycerols
- tetrahydrobiopterin
- hydroxylases
- bh4
-
tetrahydrobiopterin-dependent
- biopterin
- pterins
- tetrahydropterins
- dihydropteridine
-
phenylketonuria
- sepiapterin
Reaction
Synonyms
AGMO, alkylglycerol mono-oxygenase, alkylglycerol monooxygenase, EC 1.14.99.17, glyceryl ether hydroxylase, glyceryl ether monooxygenase, glyceryl ether oxidase, glyceryl ether oxygenase, glyceryl ether-cleaving enzyme, glyceryl etherase, glyceryl-ether cleaving enzyme, O-alkylglycerol monooxygenase, oxygenase, glyceryl ether mono-, PRUB680
ECTree
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Systematic Name
Systematic Name on EC 1.14.16.5 - alkylglycerol monooxygenase
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1-alkyl-sn-glycerol,tetrahydrobiopteridine:oxygen oxidoreductase
The enzyme cleaves alkylglycerols, but does not cleave alkenylglycerols (plasmalogens). Requires non-heme iron [7], reduced glutathione and phospholipids for full activity. The product spontaneously breaks down to form a fatty aldehyde and glycerol. The co-product, 4a-hydroxytetrahydropteridine, is rapidly dehydrated to 6,7-dihydropteridine, either spontaneously or by EC 4.2.1.96, 4a-hydroxytetrahydrobiopterin dehydratase.