1.14.14.54: phenylacetate 2-hydroxylase

This is an abbreviated version!
For detailed information about phenylacetate 2-hydroxylase, go to the full flat file.

Reaction

Synonyms

CYP504, PA 2-hydroxylase, phaA, PhAc 2-hydroxylase, phacA, phenylacetate, NAD(P):oxygen oxidoreductase (2-hydroxylating)

ECTree

1 Oxidoreductases

1.14 Acting on paired donors, with incorporation or reduction of molecular oxygen

1.14.14 With reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen into the other donor

1.14.14.54 phenylacetate 2-hydroxylase

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Results	in table
3	AA Sequence
1	Cofactor
1	Expression
1	General Information
3	Natural Substrates/ Products (Substrates)
3	Organism
4	Pathway
2	Protein Variants
1	Reaction
3	Reference
1	Source Tissue
3	Substrates and Products (Substrate)
10	Synonyms
1	Systematic Name

Reference

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Reference on EC 1.14.14.54 - phenylacetate 2-hydroxylase

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742770

Rodriguez-Saiz, M.; Barredo, J.L.; Moreno, M.A.; Fernandez-Canon, J.M.; Penalva, M.A.; Diez, B.

Reduced function of a phenylacetate-oxidizing cytochrome p450 caused strong genetic improvement in early phylogeny of penicillin-producing strains

J. Bacteriol.

183

5465-5471

2001

Penicillium chrysogenum (Q9URR6), Penicillium chrysogenum, Penicillium chrysogenum NRRL 1951 (Q9URR6)

11544206

742821

Mingot, J.; Pe�alva, M.; Fernandez-Canon, J.

Disruption of phacA, an Aspergillus nidulans gene encoding a novel cytochrome P450 monooxygenase catalyzing phenylacetate 2-hydroxylation, results in penicillin overproduction

J. Biol. Chem.

274

14545-14550

1999

Aspergillus nidulans (Q9Y7G5), Aspergillus nidulans

10329644