1.14.13.179: methylxanthine N3-demethylase
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Reaction
Synonyms
ndmB
ECTree
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Systematic Name
Systematic Name on EC 1.14.13.179 - methylxanthine N3-demethylase
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theobromine:oxygen oxidoreductase (N3-demethylating)
A non-heme iron oxygenase. The enzyme from the bacterium Pseudomonas putida shares an NAD(P)H-FMN reductase subunit with EC 1.14.13.178, methylxanthine N1-demethylase, and has higher activity with NADH than with NADPH [1]. Also demethylates caffeine and theophylline with lower efficiency. Forms part of the degradation pathway of methylxanthines.