1.1.98.7: Ser-type anaerobic sulfatase-maturating enzyme
This is an abbreviated version!
For detailed information about Ser-type anaerobic sulfatase-maturating enzyme, go to the full flat file.
Reaction
Synonyms
anaerobic sulfatase-maturating enzyme, anSME, AtsB, cpe0635, nSMEcpe, Ser-type anaerobic sulfatase-maturating enzyme
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Natural Substrates Products
Natural Substrates Products on EC 1.1.98.7 - Ser-type anaerobic sulfatase-maturating enzyme
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REACTION DIAGRAM
S-adenosyl-L-methionine + a [Klebsiella pneumoniae sulfatase]-L-serine
[Klebsiella pneumoniae sulfatase]-3-oxo-L-alanine + 5'-deoxyadenosine + L-methionine
the atsB gene product plays a posttranslational role that is essential for the sulfatase to gain its catalytic activity
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S-adenosyl-L-methionine + a [sulfatase]-L-serine
a [sulfatase]-3-oxo-L-alanine + 5'-deoxyadenosine + L-methionine
S-adenosyl-L-methionine + [periplasmic sulfatase AtsA]-L-serine
[periplasmic sulfatase AtsA]-3-oxo-L-alanine + 5'-deoxyadenosine + L-methionine
the enzyme is strictly required for modification of Ser72 in the periplasmic sulfatase AtsA of Klebsiella pneumoniae. AtsB-mediated formation of 3-oxo-L-alanine is dependent on the signal peptide of AtsA
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a [sulfatase]-3-oxo-L-alanine + 5'-deoxyadenosine + L-methionine
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?
S-adenosyl-L-methionine + a [sulfatase]-L-serine
a [sulfatase]-3-oxo-L-alanine + 5'-deoxyadenosine + L-methionine
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?