EC Number |
Recommended Name |
Source Tissue |
Reference |
---|
3.6.1.56 | 2-hydroxy-dATP diphosphatase |
embryonic stem cell |
high level of activity |
715424 |
7.6.2.2 | ABC-type xenobiotic transporter |
embryonic stem cell |
W9.5 ES cells |
210397 |
3.1.1.23 | acylglycerol lipase |
embryonic stem cell |
- |
-, 750615 |
1.3.99.23 | all-trans-retinol 13,14-reductase |
embryonic stem cell |
- |
763769 |
3.4.22.15 | cathepsin L |
embryonic stem cell |
- |
697238 |
2.7.11.12 | cGMP-dependent protein kinase |
embryonic stem cell |
- |
762478 |
2.3.1.6 | choline O-acetyltransferase |
embryonic stem cell |
- |
737113 |
3.1.1.8 | cholinesterase |
embryonic stem cell |
BChE expression is constant during differentiation, decreasing at later differentiation stages, expression analysis, overview |
691739 |
2.7.3.2 | creatine kinase |
embryonic stem cell |
embryonic stem cell-derived cardiomyocytes |
674384 |
3.1.21.10 | crossover junction endodeoxyribonuclease |
embryonic stem cell |
- |
683407 |
1.14.19.20 | DELTA7-sterol 5(6)-desaturase |
embryonic stem cell |
- |
-, 745646 |
2.1.1.37 | DNA (cytosine-5-)-methyltransferase |
embryonic stem cell |
- |
705118, 706526 |
6.5.1.1 | DNA ligase (ATP) |
embryonic stem cell |
- |
716335 |
1.14.11.51 | DNA N6-methyladenine demethylase |
embryonic stem cell |
- |
736883 |
2.7.7.6 | DNA-directed RNA polymerase |
embryonic stem cell |
in embryonic stem cells, silent developmental regulator genes that are repressed by Polycomb are associated with a form of RNAPII that can elongate through coding regions but that lacks the post-translational modifications that are important for coupling RNA synthesis to co-transcriptional maturation |
703458 |
6.3.4.3 | formate-tetrahydrofolate ligase |
embryonic stem cell |
- |
662447 |
6.3.1.2 | glutamine synthetase |
embryonic stem cell |
- |
673247 |
2.1.2.1 | glycine hydroxymethyltransferase |
embryonic stem cell |
- |
704435 |
2.3.1.97 | glycylpeptide N-tetradecanoyltransferase |
embryonic stem cell |
- |
704940 |
2.3.1.48 | histone acetyltransferase |
embryonic stem cell |
- |
702861, 719241 |
2.3.1.48 | histone acetyltransferase |
embryonic stem cell |
E14.1, 129/Ola cells |
702855 |
3.4.21.108 | HtrA2 peptidase |
embryonic stem cell |
- |
670241 |
2.4.2.8 | hypoxanthine phosphoribosyltransferase |
embryonic stem cell |
- |
737120 |
2.7.1.127 | inositol-trisphosphate 3-kinase |
embryonic stem cell |
Itpkb protein level is increased upon differentiation of human embryonic stem cells |
737402 |
3.4.21.118 | kallikrein 8 |
embryonic stem cell |
- |
697185 |
1.1.1.103 | L-threonine 3-dehydrogenase |
embryonic stem cell |
- |
723777 |
1.1.1.103 | L-threonine 3-dehydrogenase |
embryonic stem cell |
embryonic stem cells are critically dependent on the amino acid threonine, and threonine catabolism via the TDH enzyme is important to the growth and metabolic state of mouse embryonic stem cells |
710562 |
1.5.1.15 | methylenetetrahydrofolate dehydrogenase (NAD+) |
embryonic stem cell |
- |
765840 |
2.7.11.24 | mitogen-activated protein kinase |
embryonic stem cell |
- |
-, 692075 |
2.7.12.2 | mitogen-activated protein kinase kinase |
embryonic stem cell |
- |
682214, 740701 |
2.4.1.150 | N-acetyllactosaminide beta-1,6-N-acetylglucosaminyltransferase |
embryonic stem cell |
native and knockout mutants, mutant cells exhibited a reduced capability in embryoglycan synthesis and adhere weakly to laminin-coated plates |
692528 |
2.7.1.60 | N-acylmannosamine kinase |
embryonic stem cell |
homozygous or heterozygous gene knock-out cells |
661666 |
2.7.7.43 | N-acylneuraminate cytidylyltransferase |
embryonic stem cell |
- |
760882 |
2.7.10.2 | non-specific protein-tyrosine kinase |
embryonic stem cell |
- |
662918, 739174, 739714 |
2.1.1.297 | peptide chain release factor N5-glutamine methyltransferase |
embryonic stem cell |
abundant mRNA expression in embryonic stem cells, weak expression in differentiated embryonic stem cells, proein is most abundant in undifferentiated embryonic stem cells |
728277 |
2.1.1.297 | peptide chain release factor N5-glutamine methyltransferase |
embryonic stem cell |
abundant mRNA expression in embryonic stem cells, weak expression in differentiated embryonic stem cells, protein is most abundant in undifferentiated embryonic stem cells |
728277 |
1.8.4.11 | peptide-methionine (S)-S-oxide reductase |
embryonic stem cell |
- |
725563 |
2.4.1.221 | peptide-O-fucosyltransferase |
embryonic stem cell |
- |
703986 |
2.4.1.221 | peptide-O-fucosyltransferase |
embryonic stem cell |
derived from blastocyst outgrowths |
704420 |
3.1.4.11 | phosphoinositide phospholipase C |
embryonic stem cell |
PLC-eta1 |
668993 |
3.1.13.4 | poly(A)-specific ribonuclease |
embryonic stem cell |
E14 |
751734 |
3.2.1.143 | poly(ADP-ribose) glycohydrolase |
embryonic stem cell |
embryonic stem cell |
666345 |
2.7.7.19 | polynucleotide adenylyltransferase |
embryonic stem cell |
- |
762055 |
2.4.1.255 | protein O-GlcNAc transferase |
embryonic stem cell |
- |
759309 |
2.3.1.B41 | protein-long-chain fatty-acyl-lysine deacylase (NAD+) |
embryonic stem cell |
- |
739132, 756407, 756879 |
2.7.1.40 | pyruvate kinase |
embryonic stem cell |
- |
708743 |
2.7.10.1 | receptor protein-tyrosine kinase |
embryonic stem cell |
- |
490538, 660919, 660921 |
2.7.7.49 | RNA-directed DNA polymerase |
embryonic stem cell |
- |
694324 |
3.1.1.116 | sn-1-specific diacylglycerol lipase |
embryonic stem cell |
- |
761722 |
4.1.2.27 | sphinganine-1-phosphate aldolase |
embryonic stem cell |
high expression rate |
727130 |
3.1.4.12 | sphingomyelin phosphodiesterase |
embryonic stem cell |
- |
730356 |
2.7.11.26 | tau-protein kinase |
embryonic stem cell |
- |
705824 |
1.8.1.9 | thioredoxin-disulfide reductase |
embryonic stem cell |
- |
658795 |
5.4.99.27 | tRNA pseudouridine13 synthase |
embryonic stem cell |
- |
747477 |
6.1.1.2 | tryptophan-tRNA ligase |
embryonic stem cell |
high expression |
728798 |
2.1.1.321 | type III protein arginine methyltransferase |
embryonic stem cell |
- |
757212 |
3.4.19.12 | ubiquitinyl hydrolase 1 |
embryonic stem cell |
- |
-, 682038 |
5.1.3.14 | UDP-N-acetylglucosamine 2-epimerase (non-hydrolysing) |
embryonic stem cell |
cell proliferation is directly correlated with GNE-expression and the cellular sialic acid concentration. Growth-related genes are differentially expressed in GNE-deficient embryonic stem cells compared to wild-type embryonic stem cells |
703905 |
2.4.2.3 | uridine phosphorylase |
embryonic stem cell |
high activity |
658264 |
1.14.11.65 | [histone H3]-dimethyl-L-lysine9 demethylase |
embryonic stem cell |
- |
753738 |
1.14.11.65 | [histone H3]-dimethyl-L-lysine9 demethylase |
embryonic stem cell |
feeder-free E14 mouse ES cells |
753737 |
2.1.1.357 | [histone H3]-lysine36 N-dimethyltransferase |
embryonic stem cell |
- |
755067 |
2.1.1.354 | [histone H3]-lysine4 N-trimethyltransferase |
embryonic stem cell |
lacking CXXC finger protein 1, cells show elevated levels of methylated histone H3-Lys4 and reduced levels of methylated histone H3-Lys9 |
674513 |
2.1.1.360 | [histone H3]-lysine79 N-trimethyltransferase |
embryonic stem cell |
- |
753177 |
2.1.1.355 | [histone H3]-lysine9 N-trimethyltransferase |
embryonic stem cell |
- |
672911, 703442 |
1.14.99.66 | [histone H3]-N6,N6-dimethyl-L-lysine4 FAD-dependent demethylase |
embryonic stem cell |
- |
-, 753349 |
1.14.99.66 | [histone H3]-N6,N6-dimethyl-L-lysine4 FAD-dependent demethylase |
embryonic stem cell |
R1 ES cells |
725961 |
2.1.1.366 | [histone H3]-N6,N6-dimethyl-lysine9 N-methyltransferase |
embryonic stem cell |
- |
759079, 759299, 759835 |
1.14.11.68 | [histone H3]-trimethyl-L-lysine27 demethylase |
embryonic stem cell |
- |
755189 |
1.14.11.69 | [histone H3]-trimethyl-L-lysine36 demethylase |
embryonic stem cell |
- |
-, 744785 |
1.14.11.67 | [histone H3]-trimethyl-L-lysine4 demethylase |
embryonic stem cell |
- |
698105, 700159, 756632 |
1.14.11.66 | [histone H3]-trimethyl-L-lysine9 demethylase |
embryonic stem cell |
- |
-, 744785 |
1.14.11.66 | [histone H3]-trimethyl-L-lysine9 demethylase |
embryonic stem cell |
feeder-free E14 mouse ES cells |
753737 |
3.2.2.19 | [protein ADP-ribosylarginine] hydrolase |
embryonic stem cell |
- |
683871 |
3.1.3.43 | [pyruvate dehydrogenase (acetyl-transferring)]-phosphatase |
embryonic stem cell |
- |
750487 |