Organism | UniProt | Comment | Textmining |
---|---|---|---|
Homo sapiens | Q15047 | - |
- |
Source Tissue | Comment | Organism | Textmining |
---|---|---|---|
embryo | embryonic stem cell | Homo sapiens | - |
embryonic stem cell | - |
Homo sapiens | - |
General Information | Comment | Organism |
---|---|---|
physiological function | embryonic stem cells exhibit high expression of the ubiquitin-conjugating enzyme UBE2K. Loss of UBE2K upregulates the trimethyltransferase SETDB1, resulting in H3K9 trimethylation and repression of neurogenic genes during differentiation | Homo sapiens |