EC Number |
Recommended Name |
Source Tissue |
Reference |
---|
2.4.1.92 | (N-acetylneuraminyl)-galactosylglucosylceramide N-acetylgalactosaminyltransferase |
astrocyte |
- |
688514 |
1.5.1.21 | 1-piperideine-2-carboxylate/1-pyrroline-2-carboxylate reductase (NADPH) |
astrocyte |
- |
743355 |
1.5.1.1 | 1-piperideine-2-carboxylate/1-pyrroline-2-carboxylate reductase [NAD(P)H] |
astrocyte |
- |
743355 |
1.2.1.105 | 2-oxoglutarate dehydrogenase system |
astrocyte |
- |
673870, 758628 |
1.1.1.149 | 20alpha-hydroxysteroid dehydrogenase |
astrocyte |
- |
763094 |
3.1.4.35 | 3',5'-cyclic-GMP phosphodiesterase |
astrocyte |
- |
652975 |
1.1.1.51 | 3(or 17)beta-hydroxysteroid dehydrogenase |
astrocyte |
major site for expression |
763514 |
1.1.1.35 | 3-hydroxyacyl-CoA dehydrogenase |
astrocyte |
activated, high level expression |
673340 |
1.13.11.6 | 3-hydroxyanthranilate 3,4-dioxygenase |
astrocyte |
- |
439372, 439373 |
2.8.1.2 | 3-mercaptopyruvate sulfurtransferase |
astrocyte |
- |
739470 |
1.1.1.357 | 3alpha-hydroxysteroid 3-dehydrogenase |
astrocyte |
- |
763094 |
1.1.1.213 | 3alpha-hydroxysteroid 3-dehydrogenase (Re-specific) |
astrocyte |
high expression and activity in astrocytes of glaucomatous optic nerve head |
668392 |
2.6.1.19 | 4-aminobutyrate-2-oxoglutarate transaminase |
astrocyte |
- |
702961 |
3.1.3.5 | 5'-nucleotidase |
astrocyte |
- |
-, 715987, 750661 |
3.1.1.23 | acylglycerol lipase |
astrocyte |
primary |
666129 |
3.4.24.86 | ADAM 17 endopeptidase |
astrocyte |
- |
639002 |
3.4.24.81 | ADAM10 endopeptidase |
astrocyte |
strain U373 MG |
669957 |
3.4.24.B10 | ADAM12 endopeptidase |
astrocyte |
- |
711642 |
3.4.24.82 | ADAMTS-4 endopeptidase |
astrocyte |
- |
668117 |
3.4.24.82 | ADAMTS-4 endopeptidase |
astrocyte |
cell culture, expression of aggrecanase-1 mRNA is induced if cells are treated with beta-amyloid |
638959 |
3.4.24.B11 | ADAMTS1 endopeptidase |
astrocyte |
- |
668117 |
3.4.24.87 | ADAMTS13 endopeptidase |
astrocyte |
in cerebral corpora amylacea, that occur in aging brains and in patients with neurodegenerative conditions |
713116 |
2.7.1.20 | adenosine kinase |
astrocyte |
astrocyte-based ADK provides a critical link between astrogliosis and neuronal dysfunction in epilepsy |
687973 |
2.7.1.20 | adenosine kinase |
astrocyte |
expressed most strongly in astrocytes |
676193 |
4.6.1.1 | adenylate cyclase |
astrocyte |
- |
681092 |
3.2.2.6 | ADP-ribosyl cyclase/cyclic ADP-ribose hydrolase |
astrocyte |
- |
731882 |
1.1.1.21 | aldose reductase |
astrocyte |
- |
-, 739113 |
2.4.3.8 | alpha-N-acetylneuraminate alpha-2,8-sialyltransferase |
astrocyte |
in primary neurons and astrocytes lacking GD3 synthase, amyloid beta-induced cell death and amyloid beta aggregation are inhibited |
689168 |
3.5.4.6 | AMP deaminase |
astrocyte |
similar level of expression of AMPD2, but greater expression of AMPD3 than in neurons |
669960 |
3.4.17.23 | angiotensin-converting enzyme 2 |
astrocyte |
transcriptional regulation of ACE2 mRNA in astrocytes is dependent on the relative concentrations of both angiotensin II and angiotensin(17) as well as on interaction with their respective receptors |
-, 667146 |
1.13.11.31 | arachidonate 12-lipoxygenase |
astrocyte |
- |
705902 |
4.3.2.1 | argininosuccinate lyase |
astrocyte |
- |
650743 |
2.4.1.38 | beta-N-acetylglucosaminylglycopeptide beta-1,4-galactosyltransferase |
astrocyte |
- |
719592 |
2.4.1.38 | beta-N-acetylglucosaminylglycopeptide beta-1,4-galactosyltransferase |
astrocyte |
primary |
688471 |
1.3.1.24 | biliverdin reductase |
astrocyte |
- |
673797 |
1.2.1.25 | branched-chain alpha-keto acid dehydrogenase system |
astrocyte |
- |
763513 |
1.2.1.25 | branched-chain alpha-keto acid dehydrogenase system |
astrocyte |
primary cortical astrocyte cultures |
-, 763378 |
2.6.1.42 | branched-chain-amino-acid transaminase |
astrocyte |
- |
640019, 640025 |
3.4.22.B25 | calpain 5 |
astrocyte |
- |
-, 732139 |
3.4.17.10 | carboxypeptidase E |
astrocyte |
cell culture |
669606 |
2.3.1.21 | carnitine O-palmitoyltransferase |
astrocyte |
isoforms CPT1a and CPT2 are expressed exclusively by astrocytes |
757462 |
3.4.22.36 | caspase-1 |
astrocyte |
- |
681931 |
3.4.22.64 | caspase-11 |
astrocyte |
- |
664925, 708506, 709623 |
3.4.22.56 | caspase-3 |
astrocyte |
primary |
700938 |
3.4.22.60 | caspase-7 |
astrocyte |
primary |
700938 |
3.4.22.61 | caspase-8 |
astrocyte |
- |
697771, 710108 |
3.4.22.61 | caspase-8 |
astrocyte |
no change in activity after irradiation |
664508 |
3.4.22.1 | cathepsin B |
astrocyte |
- |
707002 |
3.4.23.5 | cathepsin D |
astrocyte |
- |
711354, 713109, 753898 |
3.4.22.27 | cathepsin S |
astrocyte |
- |
696995 |
3.4.18.1 | cathepsin X |
astrocyte |
- |
683448 |
1.14.15.15 | cholestanetriol 26-monooxygenase |
astrocyte |
primary astrocytes express different sterol hydroxylases and are able to uptake exogenous 27-hydroxycholesterol |
705935 |
1.14.14.25 | cholesterol 24-hydroxylase |
astrocyte |
- |
-, 705920, 712120 |
1.14.14.25 | cholesterol 24-hydroxylase |
astrocyte |
in normal brain |
659374 |
1.14.14.25 | cholesterol 24-hydroxylase |
astrocyte |
primary |
712816 |
2.3.1.6 | choline O-acetyltransferase |
astrocyte |
- |
737113 |
2.7.7.15 | choline-phosphate cytidylyltransferase |
astrocyte |
- |
-, 721714 |
2.8.2.17 | chondroitin 6-sulfotransferase |
astrocyte |
- |
738897 |
2.7.3.2 | creatine kinase |
astrocyte |
- |
737427, 761135 |
4.2.1.22 | cystathionine beta-synthase |
astrocyte |
cystathionine beta-synthase is associated with the generation and/or differentiation of the radial glia/astrocyte lineage cells in the developing central nervous system |
664879 |
4.4.1.1 | cystathionine gamma-lyase |
astrocyte |
- |
710063 |
3.4.11.3 | cystinyl aminopeptidase |
astrocyte |
- |
753121 |
7.1.1.9 | cytochrome-c oxidase |
astrocyte |
cortical astrocyte. Differential, cell-type specific expression of enzyme subunit IV isoform 2 in cortical astrocytes and cerebellar neurons. Presence of subunit IV isoform 2 suppresses the sensitivity of enzyme to its allosteric regulator ATP and overrules the regulation by the cellular energy level. Pivotal role of enzyme as an oxygen sensor in brain |
675529 |
1.4.3.3 | D-amino-acid oxidase |
astrocyte |
- |
674360, 687746, 711720 |
1.4.3.3 | D-amino-acid oxidase |
astrocyte |
in lower brain stem and cerebellum, as well as type-1 astrocytes from cerebral cortex and the cerebellum |
712324 |
3.4.24.71 | endothelin-converting enzyme 1 |
astrocyte |
- |
684002 |
3.4.24.71 | endothelin-converting enzyme 1 |
astrocyte |
lower expression of ECE-1 |
710094 |
1.16.3.1 | ferroxidase |
astrocyte |
of cortex |
689209 |
1.14.13.8 | flavin-containing monooxygenase |
astrocyte |
prepared from forebrain of 1-day old Swiss Webster mice |
440389 |
3.4.21.75 | Furin |
astrocyte |
primary cortical |
-, 732368 |
2.3.2.2 | gamma-glutamyltransferase |
astrocyte |
- |
755785 |
3.4.24.35 | gelatinase B |
astrocyte |
- |
710106, 734590 |
3.4.24.35 | gelatinase B |
astrocyte |
enzyme expression is slightly induced by HIV and strongly induced by TNF alpha, while matrix metalloproteinase MMP-2 and tissue inhibitor of metalloproteinase-1 and tissue inhibitor of metalloproteinase-2 are only slightly affected. Astrocytes are a major source of enzyme in the inflamed brain |
670149 |
3.4.24.35 | gelatinase B |
astrocyte |
secretion, induced by interleukin-1beta |
683874 |
3.1.3.9 | glucose-6-phosphatase |
astrocyte |
- |
750367 |
3.1.3.9 | glucose-6-phosphatase |
astrocyte |
low enzyme activities |
649729 |
3.1.3.9 | glucose-6-phosphatase |
astrocyte |
primary |
665603 |
2.4.1.17 | glucuronosyltransferase |
astrocyte |
- |
721077 |
2.4.1.174 | glucuronylgalactosylproteoglycan 4-beta-N-acetylgalactosaminyltransferase |
astrocyte |
- |
759849 |
3.4.17.21 | Glutamate carboxypeptidase II |
astrocyte |
- |
669923, 669962, 670363, 670397, 701258, 731257, 752980 |
3.4.17.21 | Glutamate carboxypeptidase II |
astrocyte |
the level of glutamate carboxypeptidase II protein (GCPII) is regulated by valproic acid, a histone deacetylase (HDAC) inhibitor, through acetylation of lysine residue in the GCPII protein in human astrocytes, U-87MG |
752648 |
1.4.1.3 | glutamate dehydrogenase [NAD(P)+] |
astrocyte |
- |
762783, 763376 |
1.4.1.3 | glutamate dehydrogenase [NAD(P)+] |
astrocyte |
high GDH2 expression level |
712431 |
1.4.1.3 | glutamate dehydrogenase [NAD(P)+] |
astrocyte |
predominantly |
656871 |
6.3.2.2 | glutamate-cysteine ligase |
astrocyte |
- |
673803 |
6.3.2.2 | glutamate-cysteine ligase |
astrocyte |
primary astrocyte |
715084 |
6.3.2.2 | glutamate-cysteine ligase |
astrocyte |
primary cell culture |
649315 |
3.5.1.2 | glutaminase |
astrocyte |
isozymes LGA and KGA |
670391 |
3.5.1.2 | glutaminase |
astrocyte |
phosphate-activated isozyme |
670129 |
6.3.1.2 | glutamine synthetase |
astrocyte |
- |
691547, 692129, 692519, 694406, 695162, 745832 |
6.3.1.2 | glutamine synthetase |
astrocyte |
astrocyte-specific glutamine synthetase |
692128 |
6.3.1.2 | glutamine synthetase |
astrocyte |
cultured cortical astrocytes maintained with endothelins show an almost complete loss of glutamine synthetase |
693781 |
6.3.1.2 | glutamine synthetase |
astrocyte |
primary |
693726 |
6.3.1.2 | glutamine synthetase |
astrocyte |
primary cell culture |
716350 |
2.6.1.64 | glutamine-phenylpyruvate transaminase |
astrocyte |
- |
288890 |
2.3.2.5 | glutaminyl-peptide cyclotransferase |
astrocyte |
- |
735715 |
1.8.5.1 | glutathione dehydrogenase (ascorbate) |
astrocyte |
perivascular |
394026 |
1.11.1.9 | glutathione peroxidase |
astrocyte |
- |
685439, 686868 |
6.3.2.3 | glutathione synthase |
astrocyte |
primary cortical astrocytes |
693731 |
1.11.1.27 | glutathione-dependent peroxiredoxin |
astrocyte |
- |
765401 |