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1-piperideine-2-carboxylate + NADPH + H+
L-pipecolate + NADP+
1-pyrroline-(4R)-hydroxy-2-carboxylate + NADPH + H+
(4R)-hydroxy-L-proline + NADP+
-
-
-
r
1-pyrroline-2-carboxylate + NADPH + H+
L-proline + NADP+
alpha-ketobutanoate + methylamine + NADPH
N-methyl-2-aminobutanoate + NADP+ + H2O
10% of the rate with pyruvate
-
-
?
alpha-ketohexanoate + methylamine + NADPH
N-methyl-2-aminohexanoate + NADP+ + H2O
23% of the rate with pyruvate
-
-
?
cis-3-hydroxy-L-proline + NADPH + H+
? + NADP+
low activity
-
-
r
cis-4-hydroxy-L-proline + NADPH + H+
? + NADP+
DELTA1-piperideine 2-carboxylate + NADH + H+
L-pipecolate + NAD+
DELTA1-piperideine 2-carboxylate + NADPH + H+
L-pipecolate + NADP+
DELTA1-piperideine-2-carboxylate + NADH
L-pipecolate + NAD+
DELTA1-piperideine-2-carboxylate + NADPH
L-pipecolate + NADP+
DELTA1-pyrrolidine 2-carboxylate + NADH + H+
L-pipecolate + NAD+
DELTA1-pyrrolidine 2-carboxylate + NADPH + H+
L-pipecolate + NADP+
DELTA1-pyrroline-2-carboxylate + NADPH
L-proline + NADP+
DELTA1-pyrroline-5-carboxylate + NADPH + H+
?
-
very little activity
-
-
r
diglutamate + NADPH + H+
?
-
very little activity
-
-
r
fluoropyruvate + methylamine + NADPH
N-methylfluoroalanine + NADP+ + H2O
14% of the rate with pyruvate
-
-
?
L-pipecolate + NADP+
1-piperideine-2-carboxylate + NADPH + H+
the reaction equilibrium favors the direction toward NADPH-dependent reduction
-
-
r
L-proline + NADP+
1-pyrroline-2-carboxylate + NADPH + H+
the reaction equilibrium favors the direction toward NADPH-dependent reduction
-
-
r
phenylpyruvate + methylamine + NADPH
N-methylphenylalanine + NADP+ + H2O
6.3% of the rate with pyruvate
-
-
?
pyruvate + methylamine
N-methylalanine
-
-
-
?
trans-3-hydroxy-L-proline + NADPH + H+
? + NADP+
moderate activity
-
-
r
additional information
?
-
1-piperideine-2-carboxylate + NADPH + H+
L-pipecolate + NADP+
-
-
-
-
r
1-piperideine-2-carboxylate + NADPH + H+
L-pipecolate + NADP+
-
-
-
-
r
1-piperideine-2-carboxylate + NADPH + H+
L-pipecolate + NADP+
-
-
-
r
1-piperideine-2-carboxylate + NADPH + H+
L-pipecolate + NADP+
the reaction equilibrium favors the direction toward NADPH-dependent reduction
-
-
r
1-piperideine-2-carboxylate + NADPH + H+
L-pipecolate + NADP+
-
-
-
-
r
1-piperideine-2-carboxylate + NADPH + H+
L-pipecolate + NADP+
-
-
-
-
r
1-pyrroline-2-carboxylate + NADPH + H+
L-proline + NADP+
-
-
-
-
r
1-pyrroline-2-carboxylate + NADPH + H+
L-proline + NADP+
-
-
-
-
r
1-pyrroline-2-carboxylate + NADPH + H+
L-proline + NADP+
-
-
-
r
1-pyrroline-2-carboxylate + NADPH + H+
L-proline + NADP+
the reaction equilibrium favors the direction toward NADPH-dependent reduction
-
-
r
1-pyrroline-2-carboxylate + NADPH + H+
L-proline + NADP+
-
-
-
-
r
1-pyrroline-2-carboxylate + NADPH + H+
L-proline + NADP+
-
-
-
-
r
cis-4-hydroxy-L-proline + NADPH + H+
? + NADP+
-
-
-
r
cis-4-hydroxy-L-proline + NADPH + H+
? + NADP+
low activity
-
-
r
DELTA1-piperideine 2-carboxylate + NADH + H+
L-pipecolate + NAD+
-
-
-
?
DELTA1-piperideine 2-carboxylate + NADH + H+
L-pipecolate + NAD+
-
-
-
?
DELTA1-piperideine 2-carboxylate + NADPH + H+
L-pipecolate + NADP+
-
-
-
-
r
DELTA1-piperideine 2-carboxylate + NADPH + H+
L-pipecolate + NADP+
-
the equilibrium position lies far toward formation of the six-membered ring structure L-pipecolate at neutral pH
-
-
r
DELTA1-piperideine 2-carboxylate + NADPH + H+
L-pipecolate + NADP+
-
-
-
r
DELTA1-piperideine 2-carboxylate + NADPH + H+
L-pipecolate + NADP+
the equilibrium position lies far toward formation of the six-membered ring structure L-pipecolate at neutral pH
-
-
r
DELTA1-piperideine 2-carboxylate + NADPH + H+
L-pipecolate + NADP+
-
-
-
r
DELTA1-piperideine 2-carboxylate + NADPH + H+
L-pipecolate + NADP+
the equilibrium position lies far toward formation of the six-membered ring structure L-pipecolate at neutral pH
-
-
r
DELTA1-piperideine 2-carboxylate + NADPH + H+
L-pipecolate + NADP+
-
-
-
?
DELTA1-piperideine 2-carboxylate + NADPH + H+
L-pipecolate + NADP+
the equilibrium position lies far toward formation of the six-membered ring structure L-pipecolate at neutral pH
-
-
?
DELTA1-piperideine 2-carboxylate + NADPH + H+
L-pipecolate + NADP+
-
-
-
r
DELTA1-piperideine 2-carboxylate + NADPH + H+
L-pipecolate + NADP+
the equilibrium position lies far toward formation of the six-membered ring structure L-pipecolate at neutral pH
-
-
r
DELTA1-piperideine 2-carboxylate + NADPH + H+
L-pipecolate + NADP+
-
-
-
?
DELTA1-piperideine 2-carboxylate + NADPH + H+
L-pipecolate + NADP+
the equilibrium position lies far toward formation of the six-membered ring structure L-pipecolate at neutral pH
-
-
?
DELTA1-piperideine-2-carboxylate + NADH
L-pipecolate + NAD+
-
-
-
-
?
DELTA1-piperideine-2-carboxylate + NADH
L-pipecolate + NAD+
-
-
-
-
?
DELTA1-piperideine-2-carboxylate + NADPH
L-pipecolate + NADP+
-
-
-
-
?
DELTA1-piperideine-2-carboxylate + NADPH
L-pipecolate + NADP+
-
-
-
-
?
DELTA1-piperideine-2-carboxylate + NADPH
L-pipecolate + NADP+
-
-
-
ir
DELTA1-piperideine-2-carboxylate + NADPH
L-pipecolate + NADP+
-
D-lysine metabolism
-
-
?
DELTA1-piperideine-2-carboxylate + NADPH
L-pipecolate + NADP+
NADH is a poor electron donor, lower activity in the reverse reaction direction
-
-
r
DELTA1-piperideine-2-carboxylate + NADPH
L-pipecolate + NADP+
NADH is a poor electron donor, lower activity in the reverse reaction direction
-
-
r
DELTA1-piperideine-2-carboxylate + NADPH
L-pipecolate + NADP+
-
-
-
?
DELTA1-piperideine-2-carboxylate + NADPH
L-pipecolate + NADP+
-
-
-
-
?
DELTA1-pyrrolidine 2-carboxylate + NADH + H+
L-pipecolate + NAD+
-
-
-
?
DELTA1-pyrrolidine 2-carboxylate + NADH + H+
L-pipecolate + NAD+
-
-
-
?
DELTA1-pyrrolidine 2-carboxylate + NADPH + H+
L-pipecolate + NADP+
-
-
-
?
DELTA1-pyrrolidine 2-carboxylate + NADPH + H+
L-pipecolate + NADP+
-
-
-
?
DELTA1-pyrroline-2-carboxylate + NADPH
L-proline + NADP+
NADH is a poor electron donor, lower activity in the reverse reaction direction
-
-
r
DELTA1-pyrroline-2-carboxylate + NADPH
L-proline + NADP+
NADH is a poor electron donor, lower activity in the reverse reaction direction
-
-
r
DELTA1-pyrroline-2-carboxylate + NADPH
L-proline + NADP+
-
-
-
?
additional information
?
-
the same enzyme catalyzes the reduction of both DELTA1-piperideine-2-carboxylate and DELTA1-pyrrolidine-2-carboxylate, but is unable to catalyze the reduction of DELTA1-pyrroline-5-carboxylate and DELTA1-piperideine-6-carboxylate, which may be regarded as double bond positional isomers of DELTA1-piperideine-2-carboxylate and DELTA1-pyrrolidine-2-carboxylate, respectively
-
-
?
additional information
?
-
PaLhpD shows 32.8%, 14.4% and 12.2% activity for trans-3-hydroxy-L-proline, cis-4-hydroxy-L-proline, and cis-3-hydroxy-L-proline as a percent of L-proline in the oxidation reaction, respectively. Both L-proline and L-pipecolate undergo NADP+-dependent oxidization, but their kcat/Km values are 500 and 350fold lower than those with 1-pyrroline-2-carboxylate and 1-piperideine-2-carboxylate, respectively. No activity with trans-4-hydroxy-D-proline, D-proline, cis-4-hydroxy-D-proline, and cis-3-hydroxy-D-proline, poor activity with trans-4-hydroxy-L-proline
-
-
?
additional information
?
-
-
poor substrates: DELTA1-pyrroline-5-carboxylate, pyroglutamate
-
-
?
additional information
?
-
enzyme is involved in the catabolism of D-lysine and D-proline, pathway overview
-
-
?
additional information
?
-
-
enzyme is involved in the catabolism of D-lysine and D-proline, pathway overview
-
-
?
additional information
?
-
substrate specificity, enzyme shows no malate or lactate dehydrogenase activity
-
-
?
additional information
?
-
-
substrate specificity, enzyme shows no malate or lactate dehydrogenase activity
-
-
?
additional information
?
-
enzyme is involved in the catabolism of D-lysine and D-proline, pathway overview
-
-
?
additional information
?
-
substrate specificity, enzyme shows no malate or lactate dehydrogenase activity
-
-
?
additional information
?
-
no substrate: alpha-ketovalerate, ammonia
-
-
?
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1-piperideine-2-carboxylate + NADPH + H+
L-pipecolate + NADP+
1-pyrroline-(4R)-hydroxy-2-carboxylate + NADPH + H+
(4R)-hydroxy-L-proline + NADP+
-
-
-
r
1-pyrroline-2-carboxylate + NADPH + H+
L-proline + NADP+
cis-4-hydroxy-L-proline + NADPH + H+
? + NADP+
-
-
-
r
DELTA1-piperideine 2-carboxylate + NADH + H+
L-pipecolate + NAD+
DELTA1-piperideine 2-carboxylate + NADPH + H+
L-pipecolate + NADP+
DELTA1-piperideine-2-carboxylate + NADH
L-pipecolate + NAD+
DELTA1-piperideine-2-carboxylate + NADPH
L-pipecolate + NADP+
DELTA1-pyrrolidine 2-carboxylate + NADH + H+
L-pipecolate + NAD+
DELTA1-pyrrolidine 2-carboxylate + NADPH + H+
L-pipecolate + NADP+
additional information
?
-
1-piperideine-2-carboxylate + NADPH + H+
L-pipecolate + NADP+
-
-
-
-
r
1-piperideine-2-carboxylate + NADPH + H+
L-pipecolate + NADP+
-
-
-
-
r
1-piperideine-2-carboxylate + NADPH + H+
L-pipecolate + NADP+
-
-
-
r
1-piperideine-2-carboxylate + NADPH + H+
L-pipecolate + NADP+
-
-
-
-
r
1-piperideine-2-carboxylate + NADPH + H+
L-pipecolate + NADP+
-
-
-
-
r
1-pyrroline-2-carboxylate + NADPH + H+
L-proline + NADP+
-
-
-
-
r
1-pyrroline-2-carboxylate + NADPH + H+
L-proline + NADP+
-
-
-
-
r
1-pyrroline-2-carboxylate + NADPH + H+
L-proline + NADP+
-
-
-
r
1-pyrroline-2-carboxylate + NADPH + H+
L-proline + NADP+
-
-
-
-
r
1-pyrroline-2-carboxylate + NADPH + H+
L-proline + NADP+
-
-
-
-
r
DELTA1-piperideine 2-carboxylate + NADH + H+
L-pipecolate + NAD+
-
-
-
?
DELTA1-piperideine 2-carboxylate + NADH + H+
L-pipecolate + NAD+
-
-
-
?
DELTA1-piperideine 2-carboxylate + NADPH + H+
L-pipecolate + NADP+
-
-
-
-
r
DELTA1-piperideine 2-carboxylate + NADPH + H+
L-pipecolate + NADP+
-
-
-
r
DELTA1-piperideine 2-carboxylate + NADPH + H+
L-pipecolate + NADP+
-
-
-
r
DELTA1-piperideine 2-carboxylate + NADPH + H+
L-pipecolate + NADP+
-
-
-
?
DELTA1-piperideine 2-carboxylate + NADPH + H+
L-pipecolate + NADP+
-
-
-
r
DELTA1-piperideine 2-carboxylate + NADPH + H+
L-pipecolate + NADP+
-
-
-
?
DELTA1-piperideine-2-carboxylate + NADH
L-pipecolate + NAD+
-
-
-
-
?
DELTA1-piperideine-2-carboxylate + NADH
L-pipecolate + NAD+
-
-
-
-
?
DELTA1-piperideine-2-carboxylate + NADPH
L-pipecolate + NADP+
-
-
-
-
?
DELTA1-piperideine-2-carboxylate + NADPH
L-pipecolate + NADP+
-
-
-
-
?
DELTA1-piperideine-2-carboxylate + NADPH
L-pipecolate + NADP+
-
D-lysine metabolism
-
-
?
DELTA1-piperideine-2-carboxylate + NADPH
L-pipecolate + NADP+
-
-
-
-
?
DELTA1-pyrrolidine 2-carboxylate + NADH + H+
L-pipecolate + NAD+
-
-
-
?
DELTA1-pyrrolidine 2-carboxylate + NADH + H+
L-pipecolate + NAD+
-
-
-
?
DELTA1-pyrrolidine 2-carboxylate + NADPH + H+
L-pipecolate + NADP+
-
-
-
?
DELTA1-pyrrolidine 2-carboxylate + NADPH + H+
L-pipecolate + NADP+
-
-
-
?
additional information
?
-
the same enzyme catalyzes the reduction of both DELTA1-piperideine-2-carboxylate and DELTA1-pyrrolidine-2-carboxylate, but is unable to catalyze the reduction of DELTA1-pyrroline-5-carboxylate and DELTA1-piperideine-6-carboxylate, which may be regarded as double bond positional isomers of DELTA1-piperideine-2-carboxylate and DELTA1-pyrrolidine-2-carboxylate, respectively
-
-
?
additional information
?
-
enzyme is involved in the catabolism of D-lysine and D-proline, pathway overview
-
-
?
additional information
?
-
-
enzyme is involved in the catabolism of D-lysine and D-proline, pathway overview
-
-
?
additional information
?
-
enzyme is involved in the catabolism of D-lysine and D-proline, pathway overview
-
-
?
Please wait a moment until the data is sorted. This message will disappear when the data is sorted.
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1.57
1-piperideine-2-carboxylate
purified recombinant His-tagged enzyme, with NADPH, pH 7.0, 30°C
0.835
1-pyrroline-(4R)-hydroxy-2-carboxylate
purified recombinant His-tagged enzyme, with NADPH, pH 7.0, 30°C
0.447
1-pyrroline-2-carboxylate
purified recombinant His-tagged enzyme, with NADPH, pH 7.0, 30°C
0.23 - 1.6
DELTA1-piperideine-2-carboxylate
0.4
DELTA1-Pyrroline-5-carboxylate
-
-
34.8
L-pipecolate
purified recombinant His-tagged enzyme, with NADPH, pH 7.0, 30°C
18.5
L-proline
purified recombinant His-tagged enzyme, with NADPH, pH 7.0, 30°C
132
trans-3-hydroxy-L-proline
purified recombinant His-tagged enzyme, with NADPH, pH 7.0, 30°C
additional information
additional information
-
0.23
DELTA1-piperideine-2-carboxylate
-
-
1.4
DELTA1-piperideine-2-carboxylate
-
at pH 6.5 temperature not specified in the publication
1.6
DELTA1-piperideine-2-carboxylate
-
at pH 6.5, temperature not specified in the publication
0.034
NADP+
pH 10.0, 35°C, with substrate L-proline
0.14
NADP+
pH 10.0, 35°C, with substrate L-pipecolate
0.034
NADPH
pH 8.0, 35°C, with substrate DELTA1-pyrroline-2-carboxylate
0.14
NADPH
pH 8.0, 35°C, with substrate DELTA1-piperideine-2-carboxylate
additional information
additional information
kinetics
-
additional information
additional information
-
kinetics
-
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0.33
purified recombinant enzyme, substrates DELTA1-pyrroline-2-carboxylate and NADH
0.49
purified recombinant His-tagged enzyme, substrate trans-3-hydroxy-L-proline , pH 7.0, 30°C
0.67
purified recombinant enzyme, substrates DELTA1-piperideine-2-carboxylate and NADH
0.679
purified recombinant His-tagged enzyme, substrate L-pipecolate, pH 7.0, 30°C
1.4
purified recombinant enzyme, substrates L-pipecolate and NADP+
1.98
purified recombinant His-tagged enzyme, substrate L-proline, pH 7.0, 30°C
12.1
purified recombinant His-tagged enzyme, substrates 1-pyrroline-(4R)-hydroxy-2-carboxylate and NADH, pH 7.0, 30°C
140
substrate pyruvate, 30°C, pH 10.0
150
substrate DELTA1-piperideine-2-carboxylate, 30°C, pH 10.0
390
substrate DELTA1-pyrroline-2-carboxylate, 30°C, pH 10.0
51
purified recombinant enzyme, substrates DELTA1-pyrroline-2-carboxylate and NADPH
92
purified recombinant enzyme, substrates DELTA1-piperideine-2-carboxylate and NADPH
42.3
purified recombinant His-tagged enzyme, substrate 1-piperideine-2-carboxylate, pH 7.0, 30°C
42.3
purified recombinant His-tagged enzyme, substrate 1-pyrroline-2-carboxylate, pH 7.0, 30°C
additional information
-
additional information
-
-
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evolution
enzyme Pyr2C reductase is a member of the ornithine cyclodeaminase/micro-crystallin superfamily and behaves similar to DkpA
metabolism
the enzyme is important in the L-pipecolate pathway, overview. Besides the pipecolate pathway, the enzyme is also involved in L-ornithine/L-glutamate/L-proline metabolism as well as sulfur-containing amino acid metabolism. There are two ways of lysine degradation, although the saccharopine pathway can be detected in the adult mouse brain, the pipecolate pathway greatly predominates in the adult mammalian brain. Pathway regulation, overview
metabolism
-
the enzyme is important in the L-pipecolate pathway, overview. Besides the pipecolate pathway, the enzyme is also involved in L-ornithine/L-glutamate/L-proline metabolism as well as sulfur-containing amino acid metabolism. There are two ways of lysine degradation, the saccharopine pathway and the pipecolate pathway, the latter dominates in the adult mammalian brain. Pathway regulation, overview
metabolism
the enzyme is important in the L-pipecolate pathway, overview. Besides the pipecolate pathway, the enzyme is also involved in L-ornithine/L-glutamate/L-proline metabolism as well as sulfur-containing amino acid metabolism. There are two ways of lysine degradation, the saccharopine pathway and the pipecolate pathway, the latter dominates in the adult mammalian brain. Pathway regulation, overview
metabolism
the enzyme is important in the L-pipecolate pathway, overview. Besides the pipecolate pathway, the enzyme is also involved in L-ornithine/L-glutamate/L-proline metabolism as well as sulfur-containing amino acid metabolism. There are two ways of lysine degradation, the saccharopine pathway and the pipecolate pathway, the latter dominates in the adult mammalian brain. Pathway regulation, overview
metabolism
the enzyme is important in the L-pipecolate pathway, overview. Besides the pipecolate pathway, the enzyme is also involved in L-ornithine/L-glutamate/L-proline metabolism as well as sulfur-containing amino acid metabolism. There are two ways of lysine degradation, the saccharopine pathway and the pipecolate pathway, the latter dominates in the adult mammalian brain. Pathway regulation, overview
metabolism
the enzyme is important in the L-pipecolate pathway, overview. Besides the pipecolate pathway, the enzyme is also involved in L-ornithine/L-glutamate/L-proline metabolism as well as sulfur-containing amino acid metabolism. There are two ways of lysine degradation, the saccharopine pathway and the pipecolate pathway, the latter dominates in the adult mammalian brain. Pathway regulation, overview
metabolism
the enzyme is not involved in the trans-3-hydroxy-L-proline pathway and the trans-4-hydroxy-L-proline pathway
physiological function
-
CRYM has the ability to strongly bind thyroid hormones in an NADPH-dependent fashion. CRYM is also an enzyme, namely ketimine reductase, which catalyzes the NAD(P)H-dependent reduction of -C=N- (imine) double bonds of a number of cyclic ketimine substrates including sulfur-containing cyclic ketimines, the enzyme has a biological function in its degradative role as a DELTA1-piperideine-2-carboxylate (P2C) reductase in the pipecolate pathway of lysine metabolism. The pipecolate pathway is the main L-lysine degradation pathway in the adult brain. Potent regulation of ketimine reductase activity by thyroid hormones
physiological function
CRYM has the ability to strongly bind thyroid hormones in an NADPH-dependent fashion. CRYM is also an enzyme, namely ketimine reductase, which catalyzes the NAD(P)H-dependent reduction of -C=N- (imine) double bonds of a number of cyclic ketimine substrates including sulfur-containing cyclic ketimines, the enzyme has a biological function in its degradative role as a DELTA1-piperideine-2-carboxylate (P2C) reductase in the pipecolate pathway of lysine metabolism. The pipecolate pathway is the main L-lysine degradation pathway in the adult brain. Potent regulation of ketimine reductase activity by thyroid hormones
physiological function
CRYM has the ability to strongly bind thyroid hormones in an NADPH-dependent fashion. CRYM is also an enzyme, namely ketimine reductase, which catalyzes the NAD(P)H-dependent reduction of -C=N- (imine) double bonds of a number of cyclic ketimine substrates including sulfur-containing cyclic ketimines, the enzyme has a biological function in its degradative role as a DELTA1-piperideine-2-carboxylate (P2C) reductase in the pipecolate pathway of lysine metabolism. The pipecolate pathway is the main L-lysine degradation pathway in the adult brain. Potent regulation of ketimine reductase activity by thyroid hormones
physiological function
CRYM has the ability to strongly bind thyroid hormones in an NADPH-dependent fashion. CRYM is also an enzyme, namely ketimine reductase, which catalyzes the NAD(P)H-dependent reduction of -C=N- (imine) double bonds of a number of cyclic ketimine substrates including sulfur-containing cyclic ketimines, the enzyme has a biological function in its degradative role as a DELTA1-piperideine-2-carboxylate (P2C) reductase in the pipecolate pathway of lysine metabolism. The pipecolate pathway is the main L-lysine degradation pathway in the adult brain. Potent regulation of ketimine reductase activity by thyroid hormones
physiological function
CRYM has the ability to strongly bind thyroid hormones in an NADPH-dependent fashion. CRYM is also an enzyme, namely ketimine reductase, which catalyzes the NAD(P)H-dependent reduction of -C=N- (imine) double bonds of a number of cyclic ketimine substrates including sulfur-containing cyclic ketimines, the enzyme has a biological function in its degradative role as a DELTA1-piperideine-2-carboxylate (P2C) reductase in the pipecolate pathway of lysine metabolism. The pipecolate pathway is the main L-lysine degradation pathway in the adult brain. Potent regulation of ketimine reductase activity by thyroid hormones
physiological function
CRYM has the ability to strongly bind thyroid hormones in an NADPH-dependent fashion. CRYM is also an enzyme, namely ketimine reductase, which catalyzes the NAD(P)H-dependent reduction of -C=N- (imine) double bonds of a number of cyclic ketimine substrates including sulfur-containing cyclic ketimines, the enzyme has a biological function in its degradative role as a DELTA1-piperideine-2-carboxylate (P2C) reductase in the pipecolate pathway of lysine metabolism. The pipecolate pathway is the main L-lysine degradation pathway in the adult brain. Potent regulation of ketimine reductase activity by thyroid hormones
additional information
-
enzymes that reduce DELTA1-pyrroline-5-carboxylate/DELTA1-piperideine-6-carboxylate (Pyr5C/P6C) are aldimine reductases, whereas enzymes that reduce DELTA1-pyrroline-2-carboxylate/DELTA1-piperideine-2-carboxylate (Pyr2C/P2C) are ketimine reductases
additional information
enzymes that reduce DELTA1-pyrroline-5-carboxylate/DELTA1-piperideine-6-carboxylate (Pyr5C/P6C) are aldimine reductases, whereas enzymes that reduce DELTA1-pyrroline-2-carboxylate/DELTA1-piperideine-2-carboxylate (Pyr2C/P2C) are ketimine reductases
additional information
enzymes that reduce DELTA1-pyrroline-5-carboxylate/DELTA1-piperideine-6-carboxylate (Pyr5C/P6C) are aldimine reductases, whereas enzymes that reduce DELTA1-pyrroline-2-carboxylate/DELTA1-piperideine-2-carboxylate (Pyr2C/P2C) are ketimine reductases
additional information
enzymes that reduce DELTA1-pyrroline-5-carboxylate/DELTA1-piperideine-6-carboxylate (Pyr5C/P6C) are aldimine reductases, whereas enzymes that reduce DELTA1-pyrroline-2-carboxylate/DELTA1-piperideine-2-carboxylate (Pyr2C/P2C) are ketimine reductases
additional information
enzymes that reduce DELTA1-pyrroline-5-carboxylate/DELTA1-piperideine-6-carboxylate (Pyr5C/P6C) are aldimine reductases, whereas enzymes that reduce DELTA1-pyrroline-2-carboxylate/DELTA1-piperideine-2-carboxylate (Pyr2C/P2C) are ketimine reductases
additional information
enzymes that reduce DELTA1-pyrroline-5-carboxylate/DELTA1-piperideine-6-carboxylate (Pyr5C/P6C) are aldimine reductases, whereas enzymes that reduce DELTA1-pyrroline-2-carboxylate/DELTA1-piperideine-2-carboxylate (Pyr2C/P2C) are ketimine reductases
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