2.7.1.138: ceramide kinase

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For detailed information about ceramide kinase, go to the full flat file.

Word Map on EC 2.7.1.138

2.7.1.138

ceramide-1-phosphate

sphingolipids

1-phosphate

sphingosine-1-phosphate

ceramidase

pleckstrin

cerkl

medicine

ceramide-induced

analysis

diagnostics

Reaction

Synonyms

acylsphingosine kinase, ceramide kinase, CERK, DCERK protein, hCERK, kinase, acylsphingosine (phosphorylating), More

ECTree

2 Transferases

2.7 Transferring phosphorus-containing groups

2.7.1 Phosphotransferases with an alcohol group as acceptor

2.7.1.138 ceramide kinase

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Results	in table
10	Activating Compound
1476	AA Sequence
9	Application
1	CAS Registry Number
31	Cloned(Commentary)
31	Cofactor
133	Disease/ Diagnostics
6	Expression
42	General Information
2	General Stability
2	IC50 Value
41	Inhibitors
3	Ki Value [mM]
26	KM Value [mM]
58	Localization
40	Metals/Ions
4	Molecular Weight [Da]
62	Natural Substrates/ Products (Substrates)
72	Organism
1	Oxidation Stability
3	Pathway
1	PDB ID
13	pH Optimum
2	pH Range
4	Posttranslational Modification
53	Protein Variants
10	Purification (Commentary)
3	Reaction
24	Reaction Type
67	Reference
128	Source Tissue
11	Specific Activity [micromol/min/mg]
3	Storage Stability
173	Substrates and Products (Substrate)
3	Subunits
72	Synonyms
1	Systematic Name
9	Temperature Optimum [°C]

Source Tissue

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Source Tissue on EC 2.7.1.138 - ceramide kinase

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cerebellar Purkinje cell

dermal microvascular endothelial cell

extraction of bone marrow and preparation of macrophages

671750, 671756, 690404

HeLa cell

Homo sapiens

671756, 675274, 691938

mouse keratinocyte cell line SP1

cell line HL-60

lung adenocarcinoma cell

glomerular

mesenchymal stem cell

Mus musculus

Q8K4Q7

bone marrow-derived mesenchymal stem cells, BM-MSCs

leukocyte

peripheral blood mononuclear cell

Homo sapiens

very high expression level in resting and low expression level in activated CD4+ cell, resting CD8+ cells, resting, CD14+ cells, higher expression level in resting and low expression level in activated CD19+ cells

661653

peritoneal macrophage

bone marrow-derived macrophage, BMDM

CD4+ and CD8+

low expression level

umbilical vein endothelial cell

Homo sapiens

690404

additional information

3 entries