2.7.1.138: ceramide kinase
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For detailed information about ceramide kinase, go to the full flat file.
Word Map on EC 2.7.1.138
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2.7.1.138
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ceramide-1-phosphate
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sphingolipids
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1-phosphate
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sphingosine-1-phosphate
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ceramidase
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pleckstrin
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cerkl
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medicine
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ceramide-induced
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analysis
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diagnostics
- 2.7.1.138
- ceramide-1-phosphate
- sphingolipids
- 1-phosphate
- sphingosine-1-phosphate
- ceramidase
-
pleckstrin
-
cerkl
- medicine
-
ceramide-induced
- analysis
- diagnostics
Reaction
Synonyms
acylsphingosine kinase, ceramide kinase, CERK, DCERK protein, hCERK, kinase, acylsphingosine (phosphorylating), More
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Application
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analysis
enzymatic assay to quantify mass levels of long chain ceramides in cellular lipid extracts
diagnostics
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putative prognostic marker in breast cancer, estrogen receptor negative patients with high ceramide kinase expression had a worse prognosis then those with low expression
medicine
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ceramide kinase is important for neutrophil homeostasis, ceramide kinase is important for the defense against Streptococcus pneumoniae infections
medicine
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potentially important therapeutic target in oncology and inflammation
medicine
CerK inhibition has potential for treating mesangioproliferative kidney diseases in humans
medicine
CerK inhibition has potential for treating mesangioproliferative kidney diseases in humans
medicine
the enzyme is a therapeutical target in breast cancer treatment due to its functional role in breast cancer recurrence