2.7.1.138: ceramide kinase

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For detailed information about ceramide kinase, go to the full flat file.

Word Map on EC 2.7.1.138

2.7.1.138

ceramide-1-phosphate

sphingolipids

1-phosphate

sphingosine-1-phosphate

ceramidase

pleckstrin

cerkl

medicine

ceramide-induced

analysis

diagnostics

Reaction

Synonyms

acylsphingosine kinase, ceramide kinase, CERK, DCERK protein, hCERK, kinase, acylsphingosine (phosphorylating), More

ECTree

2 Transferases

2.7 Transferring phosphorus-containing groups

2.7.1 Phosphotransferases with an alcohol group as acceptor

2.7.1.138 ceramide kinase

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Results	in table
10	Activating Compound
1476	AA Sequence
9	Application
1	CAS Registry Number
31	Cloned(Commentary)
31	Cofactor
133	Disease/ Diagnostics
6	Expression
42	General Information
2	General Stability
2	IC50 Value
41	Inhibitors
3	Ki Value [mM]
26	KM Value [mM]
58	Localization
40	Metals/Ions
4	Molecular Weight [Da]
62	Natural Substrates/ Products (Substrates)
72	Organism
1	Oxidation Stability
3	Pathway
1	PDB ID
13	pH Optimum
2	pH Range
4	Posttranslational Modification
53	Protein Variants
10	Purification (Commentary)
3	Reaction
24	Reaction Type
67	Reference
128	Source Tissue
11	Specific Activity [micromol/min/mg]
3	Storage Stability
173	Substrates and Products (Substrate)
3	Subunits
72	Synonyms
1	Systematic Name
9	Temperature Optimum [°C]

Purification

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Purification on EC 2.7.1.138 - ceramide kinase

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Rattus norvegicus

640965

anti-FLAG M2 affinity gel chromatography

Homo sapiens

671756

as a C-terminal fusion to maltose binding protein, MBP-Cerk was purified on amylose resin

Homo sapiens

690404

by affinity chromatography

Homo sapiens

Q8TCT0

699827

Ni-NTA affinity column chromatography

Homo sapiens

694006

nickel-nitriloacetate resin chromatography

Homo sapiens

690671

partially, subcellular fractionation

2 entries

Sepharose-bead chromatography and Bio-Spin 6 column chromatography

Triton X-114, Mono Q