EC Number   |
Disease |
PubMed ID |
Title of Publication |
Category |
Confidence Level |
|---|
   3.4.22.B80 | COVID-19 |
32726803 |
Papain-like protease regulates SARS-CoV-2 viral spread and innate immunity. |
causal interaction
ongoing research
therapeutic application
unassigned |
1
2
4
0 |
| 3.4.22.B80 | COVID-19 |
32845033 |
Mechanism and inhibition of the papain-like protease, PLpro, of SARS-CoV-2. |
causal interaction
unassigned |
2
0 |
| 3.4.22.B80 | COVID-19 |
33304884 |
Repurposing Known Drugs as Covalent and Non-covalent Inhibitors of the SARS-CoV-2 Papain-Like Protease. |
therapeutic application
unassigned |
4
0 |
| 3.4.22.B80 | COVID-19 |
33675510 |
Exploring naphthyl derivatives as SARS-CoV papain-like protease (PLpro) inhibitors and its implications in COVID-19 drug discovery. |
causal interaction
therapeutic application
unassigned |
2
3
0 |
| 3.4.22.B80 | COVID-19 |
34364941 |
Repurposing clinically approved drugs for COVID-19 treatment targeting SARS-CoV-2 papain-like protease. |
therapeutic application
unassigned |
4
0 |
| 3.4.22.B80 | COVID-19 |
34420183 |
Evaluating Stability and Activity of SARS-CoV-2 PLpro for High-throughput Screening of Inhibitors. |
causal interaction
therapeutic application
unassigned |
3
2
0 |
| 3.4.22.B80 | COVID-19 |
34456530 |
In silico molecular docking of SARS-CoV-2 surface proteins with microbial non-ribosomal peptides: identification of potential drugs. |
unassigned |
0 |
| 3.4.22.B80 | Hepatitis C |
33984267 |
Hepatitis C virus drugs that inhibit SARS-CoV-2 papain-like protease synergize with remdesivir to suppress viral replication in cell culture. |
ongoing research
therapeutic application
unassigned |
1
2
0 |
| 3.4.22.B80 | Infections |
25320088 |
Crystal structure of the Middle East respiratory syndrome coronavirus (MERS-CoV) papain-like protease bound to ubiquitin facilitates targeted disruption of deubiquitinating activity to demonstrate its role in innate immune suppression. |
causal interaction
unassigned |
1
0 |
| 3.4.22.B80 | Infections |
32726803 |
Papain-like protease regulates SARS-CoV-2 viral spread and innate immunity. |
causal interaction
ongoing research
therapeutic application
unassigned |
1
2
4
0 |
