EC Number   |
Disease |
PubMed ID |
Title of Publication |
Category |
Confidence Level |
|---|
   1.6.2.4 | 3alpha(or 20beta)-hydroxysteroid dehydrogenase deficiency |
20417277 |
Gas chromatography/mass spectrometry (GC/MS) remains a pre-eminent discovery tool in clinical steroid investigations even in the era of fast liquid chromatography tandem mass spectrometry (LC/MS/MS). |
causal interaction
unassigned |
4
0 |
| 1.6.2.4 | 3alpha(or 20beta)-hydroxysteroid dehydrogenase deficiency |
21874273 |
Role of a Disordered Steroid Metabolome in the Elucidation of Sterol and Steroid Biosynthesis. |
causal interaction
therapeutic application
unassigned |
3
1
0 |
| 1.6.2.4 | 3alpha(or 20beta)-hydroxysteroid dehydrogenase deficiency |
25096886 |
Novel insight into etiology, diagnosis and management of primary adrenal insufficiency. |
causal interaction
unassigned |
4
0 |
| 1.6.2.4 | 3alpha(or 20beta)-hydroxysteroid dehydrogenase deficiency |
26297192 |
Estimation of reference curves for the urinary steroid metabolome in the first year of life in healthy children: Tracing the complexity of human postnatal steroidogenesis. |
therapeutic application
unassigned |
1
0 |
| 1.6.2.4 | Aberrant Crypt Foci |
24552495 |
Role of Hepatic and Intestinal P450 Enzymes in the Metabolic Activation of the Colon Carcinogen Azoxymethane in Mice. |
ongoing research
unassigned |
3
0 |
| 1.6.2.4 | Adenocarcinoma |
7577460 |
Importance of P450 reductase activity in determining sensitivity of breast tumour cells to the bioreductive drug, tirapazamine (SR 4233). |
diagnostic usage
ongoing research
therapeutic application
unassigned |
1
4
1
0 |
| 1.6.2.4 | Adenocarcinoma |
18191533 |
Overexpression of cytochrome P450 NADPH reductase sensitises MDA 231 breast carcinoma cells to 5-fluorouracil: Possible mechanisms involved. |
causal interaction
ongoing research
therapeutic application
unassigned |
1
3
2
0 |
| 1.6.2.4 | Adenocarcinoma |
27940401 |
DNA damage induced by NADPH cytochrome P450 reductase-activated idarubicin in sensitive and multidrug resistant MCF7 breast cancer cells. |
ongoing research
therapeutic application
unassigned |
3
1
0 |
| 1.6.2.4 | Adrenal Hyperplasia, Congenital |
15220035 |
Congenital adrenal hyperplasia caused by mutant P450 oxidoreductase and human androgen synthesis: analytical study. |
causal interaction
ongoing research
unassigned |
3
3
0 |
| 1.6.2.4 | Adrenal Hyperplasia, Congenital |
15666853 |
A male twin infant with skull deformity and elevated neonatal 17-hydroxyprogesterone: a prismatic case of P450 oxidoreductase deficiency. |
causal interaction
unassigned |
1
0 |
