EC Number   |
Disease |
PubMed ID |
Title of Publication  |
Category |
Confidence Level |
|---|
   3.4.22.52 | Muscular Atrophy |
34319828 |
A semiautomated measurement of muscle fiber size using the Imaris software. |
causal interaction
unassigned |
2
0 |
| 3.4.22.52 | Alzheimer Disease |
25476568 |
Accumulation of ?-synuclein in dementia with Lewy bodies is associated with decline in the ?-synuclein-degrading enzymes kallikrein-6 and calpain-1. |
diagnostic usage
ongoing research
unassigned |
3
1
0 |
| 3.4.22.52 | Dementia |
25476568 |
Accumulation of ?-synuclein in dementia with Lewy bodies is associated with decline in the ?-synuclein-degrading enzymes kallikrein-6 and calpain-1. |
diagnostic usage
ongoing research
unassigned |
3
1
0 |
| 3.4.22.52 | Sepsis |
27880847 |
Activation of Both the Calpain and Ubiquitin-Proteasome Systems Contributes to Septic Cardiomyopathy through Dystrophin Loss/Disruption and mTOR Inhibition. |
causal interaction
diagnostic usage
therapeutic application
unassigned |
2
3
1
0 |
| 3.4.22.52 | Alzheimer Disease |
9296555 |
Active site-directed antibodies identify calpain II as an early-appearing and pervasive component of neurofibrillary pathology in Alzheimer's disease. |
causal interaction
ongoing research
unassigned |
3
1
0 |
| 3.4.22.52 | Cataract |
2998702 |
Age-related changes of calpain II and alpha-crystallin in the lens of hereditary cataract (Nakano) mouse. |
causal interaction
ongoing research
therapeutic application
unassigned |
4
1
1
0 |
| 3.4.22.52 | Carcinogenesis |
23831472 |
ALLN hinders HCT116 tumor growth through Bax-dependent apoptosis. |
causal interaction
unassigned |
4
0 |
| 3.4.22.52 | Neoplasms |
23831472 |
ALLN hinders HCT116 tumor growth through Bax-dependent apoptosis. |
causal interaction
unassigned |
4
0 |
| 3.4.22.52 | Brain Injuries, Traumatic |
24929209 |
Alpha II Spectrin breakdown products in immature Sprague Dawley rat hippocampus and cortex after traumatic brain injury. |
unassigned |
0 |
| 3.4.22.52 | Cataract |
8395520 |
alpha-Crystallin chaperone activity is reduced by calpain II in vitro and in selenite cataract. |
ongoing research
unassigned |
3
0 |
