EC Number   |
General Information |
Reference |
|---|
   3.4.22.16 | physiological function |
cathepsin H is involved in the surfactant protein B production |
718296 |
| 3.4.22.16 | physiological function |
cathepsin H mediates the processing of talin and regulates migration of prostate cancer cells |
732111 |
| 3.4.22.16 | physiological function |
cathepsin H plays a role in enkephalin and galanin peptide neurotransmitter production |
732360 |
| 3.4.22.16 | physiological function |
profilaggrin to filaggrin processing is complex, requiring dephosphorylation and numerous proteolytic events, several proteases have been identified that cleave profilaggrin at specific sites, releasing the filaggrin monomers and both the N- and C-termini, including cathepsin H. CTSH is a differentiation-dependent protease coexpressed with filaggrin |
-, 753961 |
| 3.4.22.16 | physiological function |
the mature enzyme is inhibited by its own prodomain after maturation cleavage. Upon activation, cathepsin H displays a distinct proteolytic activity among the papain superfamily, functioning predominantly as an aminopeptidase that cleaves a single N-terminal residue from a polypeptide chain. Cathepsin H has also been shown to act as an endopeptidase, although with much lower efficiency |
755176 |
