Inhibitors | Comment | Organism | Structure |
---|---|---|---|
diethyldicarbonate | 80% inactivation after treatment with 5 mM diethyldicarbonate for 25 min, biphasic inactivation, 40-50% inactivation in first phase, 1-2 histidine residues are acylated by diethyldicarbonate, 250 mM malate provides complete protection, 50% protection with 50 mM MgSO4, 55% enzyme activity is restored with 0.5 M hydroxylamine | Ascaris suum |
Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
---|---|---|---|---|---|---|
(S)-malate + NAD+ | Ascaris suum | - |
CO2 + pyruvate + NADH | - |
? | |
Oxaloacetate | Ascaris suum | - |
CO2 + pyruvate | - |
ir |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Ascaris suum | - |
- |
- |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
(S)-malate + NAD+ | - |
Ascaris suum | CO2 + pyruvate + NADH | - |
? | |
(S)-malate + NAD+ | - |
Ascaris suum | CO2 + pyruvate + NADH | - |
r | |
Oxaloacetate | - |
Ascaris suum | CO2 + pyruvate | - |
ir |
Cofactor | Comment | Organism | Structure |
---|---|---|---|
NAD+ | - |
Ascaris suum |