Inhibitors | Comment | Organism | Structure |
---|---|---|---|
(E)-3-(4-((3R,5R,7R)-adamantan-1-yl)phenoxy)-N-(5-(piperidine-1-carbonyl)-1,4-dihydroindeno[1,2-c]pyrazol-3-yl) acrylamide | - |
Homo sapiens |
Localization | Comment | Organism | GeneOntology No. | Textmining |
---|---|---|---|---|
mitochondrion | - |
Homo sapiens | 5739 | - |
Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
---|---|---|---|---|---|---|
(S)-malate + NAD+ | Homo sapiens | - |
oxaloacetate + NADH + H+ | - |
? |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Homo sapiens | P40926 | - |
- |
Source Tissue | Comment | Organism | Textmining |
---|---|---|---|
4T1 cell | - |
Homo sapiens | - |
breast cancer cell line | - |
Homo sapiens | - |
MCF-7 cell | - |
Homo sapiens | - |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
(S)-malate + NAD+ | - |
Homo sapiens | oxaloacetate + NADH + H+ | - |
? |
Synonyms | Comment | Organism |
---|---|---|
malate dehydrogenase 2 | - |
Homo sapiens |
MDH2 | - |
Homo sapiens |
IC50 Value | IC50 Value Maximum | Comment | Organism | Inhibitor | Structure |
---|---|---|---|---|---|
0.000059 | - |
pH and temperature not specified in the publication | Homo sapiens | (E)-3-(4-((3R,5R,7R)-adamantan-1-yl)phenoxy)-N-(5-(piperidine-1-carbonyl)-1,4-dihydroindeno[1,2-c]pyrazol-3-yl) acrylamide |