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Information on EC 1.14.13.247 - stachydrine N-demethylase

for references in articles please use BRENDA:EC1.14.13.247

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IUBMB Comments

The enzyme, characterized from the bacterium Sinorhizobium meliloti 1021, consists of three different types of subunits. The catalytic unit contains a Rieske [2Fe-2S] iron-sulfur cluster, and catalyses the monooxygenation of a methyl group. The resulting N-methoxyl group is unstable and decomposes spontaneously to form formaldehyde. The other subunits are involved in the transfer of electrons from NAD(P)H to the catalytic subunit.

The enzyme appears in viruses and cellular organisms

Synonyms
stachydrine demethylase, more

REACTION
REACTION DIAGRAM
COMMENTARY hide
ORGANISM
UNIPROT
LITERATURE
L-proline betaine + NAD(P)H + H+ + O2 = N-methyl-L-proline + formaldehyde + NAD(P)+ + H2O
show the reaction diagram
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PATHWAY SOURCE
PATHWAYS
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Highest Expressing Human Cell Lines
Cell Line Links Gene Links