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BRENDA support

Information on EC 1.1.1.255 - mannitol dehydrogenase

for references in articles please use BRENDA:EC1.1.1.255

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IUBMB Comments

The enzyme from Apium graveolens (celery) oxidizes alditols with a minimum requirement of 2R chirality at the carbon adjacent to the primary carbon undergoing the oxidation. The enzyme is specific for NAD+ and does not use NADP+.

The expected taxonomic range for this enzyme is: Bacteria, Eukaryota

Synonyms
mannitol dehydrogenase, mannitol:mannose 1-oxidoreductase, nad-dependent mannitol dehydrogenase, mannitol 1-oxidoreductase, more

REACTION
REACTION DIAGRAM
COMMENTARY hide
ORGANISM
UNIPROT
LITERATURE
D-mannitol + NAD+ = D-mannose + NADH + H+
show the reaction diagram
The enzyme from Apium graveolens (celery) oxidizes alditols with a minimum requirement of 2R chirality at the carbon adjacent to the primary carbon undergoing the oxidation. The enzyme is specific for NAD+ and does not use NADP+
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PATHWAY SOURCE
PATHWAYS
MetaCyc
mannitol degradation II
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