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EC 1.14.11.57 Details
EC number
1.14.11.57
Accepted name
L-proline trans-4-hydroxylase
Reaction
L-proline + 2-oxoglutarate + O2 = trans-4-hydroxy-L-proline + succinate + CO2
Systematic name
L-proline,2-oxoglutarate:oxygen oxidoreductase (trans-4-hydroxylating)
Comment
Requires Fe2+ and ascorbate. The enzyme, isolated from multiple bacterial species, only produces trans-4-hydroxy-L-proline (cf. EC 1.14.11.56, L-proline cis-4-hydroxylase).
History
created 2017
EC Tree
1.14.11.5 created 1972, deleted 1976