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EC 1.14.13.188 Details
EC number
1.14.13.188
Accepted name
6-deoxyerythronolide B hydroxylase
Reaction
6-deoxyerythronolide B + NADPH + H+ + O2 = erythronolide B + NADP+ + H2O
Other name(s)
DEB hydroxylase,
eryF (gene name),
P450(eryF),
CYP107A1
Systematic name
6-deoxyerythronolide-B,NADPH:oxygen oxidoreductase
Comment
A heme-thiolate protein (P-450). Isolated from the bacterium Saccharopolyspora erythraea. The enzyme is involved in the biosynthesis of the antibiotic erythromycin.
History
created 2014, deleted 2018
EC Tree
1.14.13.45 created 1992, deleted 2003